Randomizované studie 2009
Duration of androgen suppression in the treatment of prostate cancer.
N Engl J Med. 2009 Jun 11;360(24):2516-27.
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Phase III postoperative adjuvant radiotherapy after radical prostatectomy compared with radical prostatectomy alone in pT3 prostate cancer with postoperative undetectable prostate-specific antigen: ARO 96-02/AUO AP 09/95.
J Clin Oncol. 2009 Jun 20;27(18):2924-30. Epub 2009 May 11.
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Standard-dose versus higher-dose prophylactic cranial irradiation (PCI) in patients with limited-stage small-cell lung cancer in complete remission after chemotherapy and thoracic radiotherapy (PCI 99-01, EORTC 22003-08004, RTOG 0212, and IFCT 99-01): a randomised clinical trial.
Lancet Oncol. 2009 May;10(5):467-74. Epub 2009 Apr 20.
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Radiotherapy and adjuvant trastuzumab in operable breast cancer: tolerability and adverse event data from the NCCTG Phase III Trial N9831.
J Clin Oncol. 2009 Jun 1;27(16):2638-44. Epub 2009 Apr 6..
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Randomized trial of induction chemotherapy with cisplatin and 5-fluorouracil with or without docetaxel for larynx preservation.
J Natl Cancer Inst. 2009 Apr 1;101(7):498-506. Epub 2009 Mar 24.
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Impact of the duration of adjuvant hormonal therapy in patients with locally advanced prostate cancer treated with radiotherapy: a secondary analysis of RTOG 85-31.
J Clin Oncol. 2009 May 1;27(13):2137-43. Epub 2009 Mar 23.
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Long-term follow-up of cancer patients receiving radiotherapy for bone metastases: results from a randomised multicentre trial.
Radiother Oncol. 2009 May;91(2):261-6. Epub 2009 Mar 21.
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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.
Lancet Oncol. 2009 May;10(5):459-66. Epub 2009 Mar 9.
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Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial.
Lancet. 2009 Mar 7;373(9666):811-20.
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Preoperative short-course radiotherapy versus combined radiochemotherapy in locally advanced rectal cancer: a multi-centre prospectively randomised study of the Berlin Cancer Society.
BMC Cancer. 2009 Feb 6;9:50.
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Phase 3 randomized trial on larynx preservation comparing sequential vs alternating chemotherapy and radiotherapy.
J Natl Cancer Inst. 2009 Feb 4;101(3):142-52. Epub 2009 Jan 27.
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Adjuvant radiotherapy for pathological T3N0M0 prostate cancer significantly reduces risk of metastases and improves survival: long-term followup of a randomized clinical trial.
J Urol. 2009 Mar;181(3):956-62. Epub 2009 Jan 23.
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A phase III trial of topotecan and whole brain radiation therapy for patients with CNS-metastases due to lung cancer.
Br J Cancer. 2009 Jan 27;100(2):291-7. Epub 2009 Jan 6.
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Radiotherapy after segmental resection of breast cancer with favorable prognostic features: 12-year follow-up results of a randomized trial.
J Clin Oncol. 2009 Feb 20;27(6):927-32. Epub 2008 Dec 29.
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Endocrine treatment, with or without radiotherapy, in locally advanced prostate cancer (SPCG-7/SFUO-3): an open randomised phase III trial.
Lancet. 2009 Jan 24;373(9660):301-8. Epub 2008 Dec 16. Erratum in: Lancet. 2009 Apr 4;373(9670):1174.
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Prophylactic cranial irradiation in extensive disease small-cell lung cancer: short-term health-related quality of life and patient reported symptoms: results of an international Phase III randomized controlled trial by the EORTC Radiation Oncology and Lung Cancer Groups.
J Clin Oncol. 2009 Jan 1;27(1):78-84. Epub 2008 Dec 1. Erratum in: J Clin Oncol. 2009 Feb 20;27(6):1002.
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Radiation Therapy Compared With Pelvic Node Resection for Node-Positive Vulvar Cancer: A Randomized Controlled Trial.
Obstetrics and Gynecology Sep 2009, vol. 114, no. 3, p. 537-546.
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A randomized trial comparing hypofractionated and conventionally fractionated three-dimensional conformal external-beam radiotherapy for localized prostate adenocarcinoma: a report on the first-year biochemical response.
Medicina, 2009, vol. 45, no. 6, p. 469-75.
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Intravaginal Brachytherapy in FIGO Stage I Low-Risk Endometrial Cancer: A Controlled Randomized Study.
International journal of gynecological cancer : Jul 2009, vol. 19, no. 5, p. 873-8.
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Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial.
Lancet 2009 Aug 1;374(9687):379-86. Epub 2009 Jul 24.
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Long-term choroidal vascular changes after iodine brachytherapy versus transpupillary thermotherapy for choroidal melanoma.
Eur J Ophthalmol. 2009 Jul-Aug;19(4):646-53.
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Quality of Life After Pelvic Radiotherapy or Vaginal Brachytherapy for Endometrial Cancer: First Results of the Randomized PORTEC-2 Trial.
Journal of Clinical Oncology: published online ahead of print 22 Jun2009.
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Radiotherapy versus Concurrent 5-Day Cisplatin and Radiotherapy in Locally Advanced Cervical Carcinoma.
Strahlentherapie und Onkologie Mar 2009 (epub: 28 Mar 2009), vol. 185, no. 3, p. 177-83.
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Prospective randomized study of selective neck dissection versus observation for N0 neck of early tongue carcinoma.
Head Neck. 2009 Jun;31(6):765-72.
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Randomized phase III trial comparing induction chemotherapy followed by radiotherapy to concomitant chemoradiotherapy for laryngeal preservation in T3M0 pyriform sinus carcinoma.
Acta Otolaryngol. 2009 May 15:1-6.
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A phase III randomised study comparing concomitant radiochemotherapy as induction versus consolidation treatment in patients with locally advanced unresectable non-small cell lung cancer.
Lung Cancer. 2009 May;64(2):187-93. Epub 2008 Sep 19.
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A randomised controlled trial of forward-planned radiotherapy (IMRT) for early breast cancer: Baseline characteristics and dosimetry results.
Radiotherapy and Oncology Volume 92, Issue 1, Pages 34-41 (July 2009).
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Impact of the boost dose of 10 Gy versus 26 Gy in patients with early stage breast cancer after a microscopically incomplete lumpectomy: 10-year results of the randomised EORTC boost trial.
Radiotherapy and Oncology Volume 90, Issue 1, Pages 80-85 (January 2009).
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Phase III Multi-Institutional Trial of Adjuvant Chemotherapy With Paclitaxel, Estramustine, and Oral Etoposide Combined With Long-Term Androgen Suppression Therapy and Radiotherapy Versus Long-Term Androgen Suppression Plus Radiotherapy Alone for High-Risk Prostate Cancer: Preliminary Toxicity Analysis of RTOG 99-02.
Int J Radiat Oncol Biol Phys. Volume 73, Issue 3, Pages 672-678 (1 March 2009).
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Final Report of Multicenter Canadian Phase III Randomized Trial of 3 Versus 8 Months of Neoadjuvant Androgen Deprivation Therapy Before Conventional-Dose Radiotherapy for Clinically Localized Prostate Cancer
Int J Radiat Oncol Biol Phys Volume 73, Issue 2, Pages 327-333 (1 February 2009).
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Effect of a Prostaglandin – Given Rectally for Prevention of Radiation-Induced Acute Proctitis – on Late Rectal Toxicity.
Strahlentherapie und Onkologie, Volume 185, Number 9 / September, 2009, 596-602.
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Predicting the Effect of Accelerated Fractionation in Postoperative Radiotherapy for Head and Neck Cancer Based On Molecular Marker Profiles: Data from a Randomized Clinical Trial.
Int J Radiat Oncol Biol Phys. 2009 Sep 2. [Epub ahead of print].
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Radiation therapy compared with pelvic node resection for node-positive vulvar cancer: a randomized controlled trial.
Obstet Gynecol. 2009 Sep;114(3):537-46.
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Early hyperbaric oxygen therapy for reducing radiotherapy side effects: early results of a randomized trial in oropharyngeal and nasopharyngeal cancer.
Int J Radiat Oncol Biol Phys. 2009 Nov 1;75(3):711-6. Epub 2009 Apr 20.
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Randomized Comparison of Whole Brain Radiotherapy, 20 Gy in Four Daily Fractions Versus 40 Gy in 20 Twice-Daily Fractions, for Brain Metastases.
Int J Radiat Oncol Biol Phys. 2009 Oct 14. [Epub ahead of print].
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Use of axillary deodorant and effect on acute skin toxicity during radiotherapy for breast cancer: a prospective randomized noninferiority trial.
Int J Radiat Oncol Biol Phys. 2009 Nov 15;75(4):1048-52. Epub 2009 Mar 26.
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A randomized trial of external beam radiotherapy versus cryoablation in patients with localized prostate cancer.
Cancer. 2009 Nov 24. [Epub ahead of print].
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Conservative surgery with and without radiotherapy in elderly patients with early-stage breast cancer: A prospective randomised multicentre trial.
Breast. 2009 Dec;18(6):373-7. Epub 2009 Nov 11.
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Chemoradiotherapy for locally advanced head and neck cancer: 10-year follow-up of the UK Head and Neck (UKHAN1) trial.
The Lancet Oncology, Early Online Publication, 28 October 2009.
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Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study.
Lancet. 2009 Jan 10;373(9658):125-36. Epub 2008 Dec 16.
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NOA-04 Randomized Phase III Trial of Sequential Radiochemotherapy of Anaplastic Glioma With Procarbazine, Lomustine, and Vincristine or Temozolomide.
J Clin Oncol. 2009 Nov 9. [Epub ahead of print].
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Radiation therapy and tamoxifen after breast-conserving surgery: Updated results of a 2x2 randomised clinical trial in patients with low risk of recurrence.
Eur J Cancer. 2009 Oct 28. [Epub ahead of print].
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Radiation therapy compared with chemotherapy for consolidation of chemotherapy-induced remission of advanced Hodgkin lymphoma: a study by the Eastern Co-operative Oncology Group (E1476) with >20 years follow-up.
Leuk Lymphoma. 2009 Oct;50(10):1632-41.
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Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival.
Lancet Oncol. 2009 Nov 6. [Epub ahead of print].
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