Randomizované studie 2015
Whole-breast irradiation with or without a boost for patients treated with breast-conserving surgery for early breast cancer: 20-year follow-up of a randomised phase 3 trial.
Lancet Oncol. 2015 Jan;16(1):47-56.
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Use of thoracic radiotherapy for extensive stage small-cell lung cancer: a phase 3 randomised controlled trial.
Lancet. 2015 Jan 3;385(9962):36-42.
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The UK HeartSpare Study (Stage IB): Randomised comparison of a voluntary breath-hold technique and prone radiotherapy after breast conserving surgery.
Radiother Oncol. 2015 Jan;114(1):66-72.
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Duration of androgen suppression before radiotherapy for localized prostate cancer: radiation therapy oncology group randomized clinical trial 9910.
J Clin Oncol. 2015 Feb 1;33(4):332-9.
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RTOG 9804: A Prospective Randomized Trial for Good-Risk Ductal Carcinoma In Situ Comparing Radiotherapy With Observation.
J Clin Oncol. 2015 Mar 1;33(7):709-15.
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Accelerated partial breast irradiation using intensity-modulated radiotherapy versus whole breast irradiation: 5-year survival analysis of a phase 3 randomised controlled trial.
Eur J Cancer. 2015 Mar;51(4):451-63.
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Phase 3 trials of stereotactic radiosurgery with or without whole-brain radiation therapy for 1 to 4 brain metastases: individual patient data meta-analysis.
Int J Radiat Oncol Biol Phys. 2015 Mar 15;91(4):710-7.
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Standard-dose versus high-dose conformal radiotherapy with concurrent and consolidation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): a randomised, two-by-two factorial phase 3 study.
Lancet Oncol. 2015 Feb;16(2):187-99.
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High-dose radiotherapy with short-term or long-term androgen deprivation in localised prostate cancer (DART01/05 GICOR): a randomised, controlled, phase 3 trial.
Lancet Oncol. 2015 Mar;16(3):320-7.
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Randomized phase III study of whole-brain radiotherapy for primary CNS lymphoma.
Neurology. 2015 Mar 24;84(12):1242-8.
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Breast-conserving surgery with or without irradiation in women aged 65 years or older with early breast cancer (PRIME II): a randomised controlled trial.
Lancet Oncol. 2015 Mar;16(3):266-73.
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Predictors of adverse cosmetic outcome in the RAPID trial: an exploratory analysis.
Int J Radiat Oncol Biol Phys. 2015 Apr 1;91(5):968-76.
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Concurrent chemo-radiation with or without induction gemcitabine, Carboplatin, and Paclitaxel: a randomized, phase 2/3 trial in locally advanced nasopharyngeal carcinoma.
Int J Radiat Oncol Biol Phys. 2015 Apr 1;91(5):952-60.
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Hyperfractionated accelerated radiation therapy (HART) of 70.6 Gy with concurrent 5-FU/Mitomycin C is superior to HART of 77.6 Gy alone in locally advanced head and neck cancer: long-term results of the ARO 95-06 randomized phase III trial.
Int J Radiat Oncol Biol Phys. 2015 Apr 1;91(5):916-24.
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Long-term results of radiation therapy oncology group 9903: a randomized phase 3 trial to assess the effect of erythropoietin on local-regional control in anemic patients treated with radiation therapy for squamous cell carcinoma of the head and neck.
Int J Radiat Oncol Biol Phys. 2015 Apr 1;91(5):907-15.
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Results of a trial of PET-directed therapy for early-stage Hodgkins lymphoma.
N Engl J Med. 2015 Apr 23;372(17):1598-607.
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Adjuvant chemotherapy for rectal cancer patients treated with preoperative (chemo)radiotherapy and total mesorectal excision: a Dutch Colorectal Cancer Group (DCCG) randomized phase III trial.
Ann Oncol. 2015 Apr;26(4):696-701.
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No Increased Risk of Second Cancer After Radiotherapy in Patients Treated for Rectal or Endometrial Cancer in the Randomized TME, PORTEC-1, and PORTEC-2 Trials.
J Clin Oncol. 2015 May 20;33(15):1640-6.
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Randomized trial comparing surgery and adjuvant radiotherapy versus concurrent chemoradiotherapy in patients with advanced, nonmetastatic squamous cell carcinoma of thehead and neck: 10-year update and subset analysis.
Cancer. 2015 May 15;121(10):1599-607.
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Acupuncture-Like Transcutaneous Electrical Nerve Stimulation Versus Pilocarpine in Treating Radiation-Induced Xerostomia: Results of RTOG 0537 Phase 3 Study.
Int J Radiat Oncol Biol Phys. 2015 Jun 1;92(2):220-7.
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Quantifying Unnecessary Normal Tissue Complication Risks due to Suboptimal Planning: A Secondary Study of RTOG 0126.
Int J Radiat Oncol Biol Phys. 2015 Jun 1;92(2):228-35.
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Long-term Results of the UCSF-LBNL Randomized Trial: Charged Particle With Helium Ion Versus Iodine-125 Plaque Therapy for Choroidal and Ciliary Body Melanoma.
Int J Radiat Oncol Biol Phys. 2015 Jun 1;92(2):376-83.
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Three-Arm Randomized Phase III Trial: Quality Aloe and Placebo Cream Versus Powder as Skin Treatment During Breast Cancer Radiation Therapy.
Clin Breast Cancer. 2015 Jun;15(3):181-190.
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Double blind randomized prospective trial of bethanechol in the prevention of radiation-induced salivary gland dysfunction in head and neck cancer patients.
Radiother Oncol. 2015 May;115(2):253-6.
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IAEA-HypoX. A randomized multicenter study of the hypoxic radiosensitizer nimorazole concomitant with accelerated radiotherapy in head and neck squamous cell carcinoma.
Radiother Oncol. 2015 Jul;116(1):15-20.
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IAEA randomised trial of optimal single dose radiotherapy in the treatment of painful bone metastases.
Radiother Oncol. 2015 Jul;116(1):10-4.
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Morbidity and mortality after surgery for cancer of the oesophagus and gastro-oesophageal junction: A randomized clinical trial of neoadjuvant chemotherapy vs. neoadjuvant chemoradiation.
Eur J Surg Oncol. 2015 Jul;41(7):920-6.
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Prospective Randomized Comparison of the Effectiveness of Radiation Therapy and Local Steroid Injection for the Treatment of Plantar Fasciitis.
Int J Radiat Oncol Biol Phys. 2015 Jul 1;92(3):659-66.
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Importance of Local Control in Early-Stage Prostate Cancer: Outcomes of Patients With Positive Post-Radiation Therapy Biopsy Results Treated in RTOG 9408.
Int J Radiat Oncol Biol Phys. 2015 Jul 15;92(4):863-73.
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Final Report of the Intergroup Randomized Study of Combined Androgen-Deprivation Therapy Plus Radiotherapy Versus Androgen-Deprivation Therapy Alone in Locally Advanced Prostate Cancer.
J Clin Oncol. 2015 Jul 1;33(19):2143-50.
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Impact of Radiotherapy When Added to Androgen-Deprivation Therapy for Locally Advanced Prostate Cancer: Long-Term Quality-of-Life Outcomes From the NCIC CTG PR3/MRC PR07 Randomized Trial.
J Clin Oncol. 2015 Jul 1;33(19):2151-7.
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Tumour regression in the randomized Stockholm III Trial of radiotherapy regimens for rectal cancer.
Br J Surg. 2015 Jul;102(8):972-8
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Stereotactic Radiosurgery With or Without Whole-Brain Radiotherapy for Brain Metastases: Secondary Analysis of the JROSG 99-1 Randomized Clinical Trial.
JAMA Oncol. 2015 Jul;1(4):457-64.
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The International Atomic Energy Agency (IAEA) randomized trial of palliative treatment of incurable locally advanced non small cell lung cancer (NSCLC) using radiotherapy (RT) and chemotherapy (CHT) in limited resource setting.
Radiother Oncol. 2015 Jul;116(1):21-6.
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Internal Mammary and Medial Supraclavicular Irradiation in Breast Cancer.
N Engl J Med. 2015 Jul 23;373(4):317-27.
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Regional Nodal Irradiation in Early-Stage Breast Cancer.
N Engl J Med. 2015 Jul 23;373(4):307-16.
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A Multicenter Randomized Trial of Ibandronate Compared With Single-Dose Radiotherapy for Localized Metastatic Bone Pain in Prostate Cancer.
J Natl Cancer Inst. 2015 Aug 4;107(10).
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Randomized multicenter follow-up trial on the effect of radiotherapy on painful heel spur (plantar fasciitis) comparing two fractionation schedules with uniform total dose: first results after three months follow-up.
Radiat Oncol. 2015 Aug 19;10:174.
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A randomized phase II/III study of adverse events between sequential (SEQ) versus simultaneous integrated boost (SIB) intensity modulated radiation therapy (IMRT) in nasopharyngeal carcinoma; preliminary result on acute adverse events.
Radiat Oncol. 2015 Aug 8;10:166.
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Hydrogel Spacer Prospective Multicenter Randomized Controlled Pivotal Trial: Dosimetric and Clinical Effects of Perirectal Spacer Application in Men Undergoing Prostate Image Guided Intensity Modulated Radiation Therapy.
Int J Radiat Oncol Biol Phys. 2015 Aug 1;92(5):971-7.
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Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial.
Lancet Oncol. 2015 Aug;16(8):979-89.
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Neoadjuvant 5-FU or Capecitabine Plus Radiation With or Without Oxaliplatin in Rectal Cancer Patients: A Phase III Randomized Clinical Trial.
J Natl Cancer Inst. 2015 Sep 14;107(11).
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Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): long-term results of a randomised controlled trial.
Lancet Oncol. 2015 Sep;16(9):1090-8.
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Induction chemoradiation in stage IIIA/N2 non-small-cell lung cancer: a phase 3 randomised trial.
Lancet. 2015 Sep 12;386(9998):1049-56.
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Adjuvant lymph-node field radiotherapy versus observation only in patients with melanoma at high risk of further lymph-node field relapse after lymphadenectomy (ANZMTG 01.02/TROG 02.01): 6-year follow-up of a phase 3, randomised controlled trial.
Lancet Oncol. 2015 Sep;16(9):1049-60.
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The DAHANCA 6 randomized trial: Effect of 6 vs 5 weekly fractions of radiotherapy in patients with glottic squamous cell carcinoma.
Radiother Oncol. 2015 Oct;117(1):91-8.
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A Phase 3 Trial of 2 Years of Androgen Suppression and Radiation Therapy With or Without Adjuvant Chemotherapy for High-Risk Prostate Cancer: Final Results of Radiation Therapy Oncology Group Phase 3 Randomized Trial NRG Oncology RTOG 9902.
Int J Radiat Oncol Biol Phys. 2015 Oct 1;93(2):294-302.
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Effects of adjuvant radiotherapy on completely resected gastric cancer: A radiation oncologists view of the ARTIST randomized phase III trial.
Radiother Oncol. 2015 Oct;117(1):171-7.
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Hydrosorb® versus control (water based spray) in the management of radio-induced skin toxicity: Results of multicentre controlled randomized trial.
Radiother Oncol. 2015 Nov;117(2):229-33.
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Mature results from a Swedish comparison study of conventional versus accelerated radiotherapy in head and neck squamous cell carcinoma - The ARTSCAN trial.
Radiother Oncol. 2015 Oct;117(1):99-105.
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Elective versus Therapeutic Neck Dissection in Node-Negative Oral Cancer.
N Engl J Med. 2015 Aug 6;373(6):521-9.
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Acute and Short-term Toxic Effects of Conventionally Fractionated vs Hypofractionated Whole-Breast Irradiation: A Randomized Clinical Trial.
JAMA Oncol. 2015 Oct;1(7):931-41.
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Locoregional treatment versus no treatment of the primary tumour in metastatic breast cancer: an open-label randomised controlled trial.
Lancet Oncol. 2015 Oct;16(13):1380-8.
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Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial.
JAMA. 2015 Dec 15;314(23):2535-43.
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