Long-Term Follow-Up of the Response-Adapted Intergroup EORTC/LYSA/FIL H10 Trial for Localized Hodgkin Lymphoma.
J Clin Oncol. 2024 Jan 1;42(1):19-25.
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Risk Modeling for Individualization of the FLAME Focal Boost Approach in External Beam Radiation Therapy for Patients With Localized Prostate Cancer.
Int J Radiat Oncol Biol Phys. 2024 Jan 1;118(1):66-73.
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Salivary Electrostimulation in the Treatment of Radiation Therapy-Induced Xerostomia (LEONIDAS-2): A Multicenter, Randomized, Double-Masked, Sham-Controlled, Phase 3 Trial.
Int J Radiat Oncol Biol Phys. 2024 Jan 1;118(1):142-153.
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Hypofractionated, Dose Escalation Radiation Therapy for High-Risk Prostate Cancer: The Safety Analysis of the Prostate Cancer Study-5, a Groupe de Radio-Oncologie Génito-Urinaire de Quebec Led Phase 3 Trial.
Int J Radiat Oncol Biol Phys. 2024 Jan 1;118(1):52-62.
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Simple versus Radical Hysterectomy in Women with Low-Risk Cervical Cancer.
N Engl J Med. 2024 Feb 29;390(9):819-829.
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Long-Term Results of Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy: The Randomized Phase II OPRA Trial.
J Clin Oncol. 2024 Feb 10;42(5):500-506.
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Severe Lymphopenia During Chemoradiation Therapy for Esophageal Cancer: Comprehensive Analysis of Randomized Phase 2B Trial of Proton Beam Therapy Versus Intensity Modulated Radiation Therapy.
Int J Radiat Oncol Biol Phys. 2024 Feb 1;118(2):368-377.
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Trimodality Therapy With Iodine-125 Brachytherapy, External Beam Radiation Therapy, and Short- or Long-Term Androgen Deprivation Therapy for High-Risk Localized Prostate Cancer: Results of a Multicenter, Randomized Phase 3 Trial (TRIP/TRIGU0907).
Int J Radiat Oncol Biol Phys. 2024 Feb 1;118(2):390-401.
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Whole-Brain Radiotherapy Alone vs Preceded by Bevacizumab, Etoposide, and Cisplatin for Untreated Brain Metastases From Breast Cancer: A Randomized Clinical Trial.
JAMA Oncol. 2024 Mar 1;10(3):325-334.
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Physician- and Patient-Reported Outcomes of the MC1635 Phase 3 Trial of Ultrahypofractionated Versus Moderately Hypofractionated Adjuvant Radiation Therapy After Breast-Conserving Surgery.
Int J Radiat Oncol Biol Phys. 2024 Mar 15;118(4):1049-1059.
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Dose-Intensified Postoperative Radiation Therapy for Prostate Cancer: Long-Term Results From the PKUFH Randomized Phase 3 Trial.
Int J Radiat Oncol Biol Phys. 2024 Mar 1;118(3):697-705.
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Intensity-Modulated Radiation Therapy Alone Versus Intensity-Modulated Radiation Therapy and Brachytherapy for Early-Stage Oropharyngeal Cancers: Results From a Randomized Controlled Trial.
Int J Radiat Oncol Biol Phys. 2024 Apr 1;118(5):1541-1551.
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Pembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): a randomised, double-blind, phase 3 clinical trial.
Lancet. 2024 Apr 6;403(10434):1341-1350.
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Alectinib in Resected ALK-Positive Non-Small-Cell Lung Cancer.
N Engl J Med. 2024 Apr 11;390(14):1265-1276.
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Omitting Axillary Dissection in Breast Cancer with Sentinel-Node Metastases.
N Engl J Med. 2024 Apr 4;390(13):1163-1175.
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Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma.
N Engl J Med. 2024 Apr 18;390(15):1359-1371.
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Streptococcus salivarius K12 Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors: A Randomized Controlled Trial.
J Clin Oncol. 2024 Apr 20;42(12):1426-1435.
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Induction Chemotherapy Followed by Radiotherapy vs Chemoradiotherapy in Nasopharyngeal Carcinoma: A Randomized Clinical Trial.
JAMA Oncol. 2024 Apr 1;10(4):456-463.
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Hyperbaric Oxygen Therapy and Late Local Toxic Effects in Patients With Irradiated Breast Cancer: A Randomized Clinical Trial.
JAMA Oncol. 2024 Apr 1;10(4):464-474.
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Cost-effectiveness of weekly adaptive radiotherapy versus standard IMRT in head and neck cancer alongside the ARTIX trial.
Radiother Oncol. 2024 Apr;193:110116.
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Short course radiotherapy versus radiochemotherapy for locally advanced rectal cancers in the elderly (UNICANCER PRODIGE 42/GERICO 12 study): Quality of life and comprehensive geriatric assessment.
Radiother Oncol. 2024 Apr;193:110144.
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Tumor volume and cancer stem cell expression as prognostic markers for high-dose loco-regional failure in head and neck squamous cell carcinoma - A DAHANCA 19 study.
Radiother Oncol. 2024 Apr;193:110149.
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Moderate hypofractionated radiotherapy for prostate cancer: 3-year toxicity results of a multicentre randomized phase 3, non-inferiority trial.
Radiother Oncol. 2024 Apr;193:110089.
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Safety Analyses of the Phase 3 VISION Trial of [177Lu]Lu-PSMA-617 in Patients with Metastatic Castration-resistant Prostate Cancer.
Eur Urol. 2024 Apr;85(4):382-391.
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Effects of Androgen Deprivation Therapy on Prostate Cancer Outcomes According to Competing Event Risk: Secondary Analysis of a Phase 3 Randomised Trial.
Eur Urol. 2024 Apr;85(4):373-381.
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Noninferiority of Hypofractionated vs Conventional Postprostatectomy Radiotherapy for Genitourinary and Gastrointestinal Symptoms: The NRG-GU003 Phase 3 Randomized Clinical Trial.
JAMA Oncol. 2024 May 1;10(5):584-591.
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Late Toxicity of Prostate Ultrahypofractionated Radiation Therapy Compared With Moderate Hypofractionation in a Randomized Trial.
Int J Radiat Oncol Biol Phys. 2024 May 1;119(1):110-118.
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Timing of High-Dose-Rate Brachytherapy With External Beam Radiation Therapy in Patients With Intermediate- and High-Risk Localized Prostate Cancer and Its Effects on Toxicity and Quality of Life: A Randomized Controlled Trial (THEPCA).
Int J Radiat Oncol Biol Phys. 2024 May 1;119(1):90-99.
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Effect of Pelvic External Beam Radiation Therapy on Bone Mineral Density: A Secondary Analysis of a Phase 3 Randomized Controlled Trial.
Int J Radiat Oncol Biol Phys. 2024 May 1;119(1):119-126.
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Pembrolizumab Versus Placebo as Adjuvant Therapy in Resected Stage IIB or IIC Melanoma: Final Analysis of Distant Metastasis-Free Survival in the Phase III KEYNOTE-716 Study.
J Clin Oncol. 2024 May 10;42(14):1619-1624.
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Laparoscopic Versus Open Hemihepatectomy: The ORANGE II PLUS Multicenter Randomized Controlled Trial.
J Clin Oncol. 2024 May 20;42(15):1799-1809.
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Effectiveness of Endoscopic Screening on Esophageal Cancer Incidence and Mortality: A 9-Year Report of the Endoscopic Screening for Esophageal Cancer in China (ESECC) Randomized Trial.
J Clin Oncol. 2024 May 10;42(14):1655-1664.
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Pembrolizumab plus concurrent chemoradiotherapy versus placebo plus concurrent chemoradiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck (KEYNOTE-412): a randomised, double-blind, phase 3 trial.
Lancet Oncol. 2024 May;25(5):572-587.
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Perioperative Nivolumab in Resectable Lung Cancer.
N Engl J Med. 2024 May 16;390(19):1756-1769.
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Improved Disease-Free Survival With Adjuvant Chemotherapy After Nephroureterectomy for Upper Tract Urothelial Cancer: Final Results of the POUT Trial.
J Clin Oncol. 2024 May 1;42(13):1466-1471.
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Induction-concurrent chemoradiotherapy with or without sintilimab in patients with locoregionally advanced nasopharyngeal carcinoma in China (CONTINUUM): a multicentre, open-label, parallel-group, randomised, controlled, phase 3 trial.
Lancet. 2024 Jun 22;403(10445):2720-2731.
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Reduced-Volume Irradiation of Uninvolved Neck in Patients With Nasopharyngeal Cancer: Updated Results From an Open-Label, Noninferiority, Multicenter, Randomized Phase III Trial.
J Clin Oncol. 2024 Jun 10;42(17):2021-2025.
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A multicentric randomized controlled phase III trial of adaptive and 18F-FDG-PET-guided dose-redistribution in locally advanced head and neck squamous cell carcinoma (ARTFORCE).
Radiother Oncol. 2024 Jul;196:110281.
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Five-Year Mortality Outcomes for Eating As Treatment (EAT), a Health Behavior Change Intervention to Improve Nutrition in Patients With Head and Neck Cancer: A Stepped-Wedge, Randomized Controlled Trial.
Int J Radiat Oncol Biol Phys. 2024 Jul 15;119(4):1166-1170.
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ESHO 1-85. Hyperthermia as an adjuvant to radiation therapy in the treatment of locally advanced breast carcinoma. A randomized multicenter study by the European Society for Hyperthermic Oncology.
Radiother Oncol. 2024 Jul;196:110313.
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Radiation Therapy With or Without Cisplatin for Local Recurrences of Endometrial Cancer: Results From an NRG Oncology/GOG Prospective Randomized Multicenter Clinical Trial.
J Clin Oncol. 2024 Jul 10;42(20):2425-2435.
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Image guided radiotherapy in curative treatment for prostate cancer. 5-year results from a randomized controlled trial (RIC-trial).
Radiother Oncol. 2024 Jul;196:110309.
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Primary Surgery Followed by Selective Chemoradiotherapy Versus Preoperative Chemoradiotherapy Followed by Surgery for Locally Advanced Rectal Cancer: A Randomized Clinical Trial.
Int J Radiat Oncol Biol Phys. 2024 Jul 1;119(3):884-895.
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Randomized Phase 3 Trial of the Hypoxia Modifier Nimorazole Added to Radiation Therapy With Benefit Assessed in Hypoxic Head and Neck Cancers Determined Using a Gene Signature (NIMRAD).
Int J Radiat Oncol Biol Phys. 2024 Jul 1;119(3):771-782.
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Randomized self-controlled study comparing open-face vs. closed immobilization masks in fractionated cranial radiotherapy.
Radiother Oncol. 2024 Jul;196:110314.
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Prostate-Specific Antigen Response to Androgen Deprivation Therapy in the Neoadjuvant Setting for High-Risk Prostate Adenocarcinoma (PIRANHA): Pooled Analysis of Two Randomized Clinical Trials.
Int J Radiat Oncol Biol Phys. 2024 Jul 1;119(3):826-831.
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Impact of Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography on Prostate Cancer Salvage Radiotherapy Management: Results from a Prospective Multicenter Randomized Phase 3 Trial (PSMA-SRT NCT03582774).
Eur Urol. 2024 Jul;86(1):52-60.
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Long-Term Quality-of-Life Outcomes After Prostate Radiation Therapy With or Without High-Dose-Rate Brachytherapy Boost: Post Hoc Analysis of TROG 03.04 RADAR.
Int J Radiat Oncol Biol Phys. 2024 Jul 1;119(3):813-825.
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Long-Term Analysis of NRG Oncology RTOG 0415: A Randomized Phase III Noninferiority Study Comparing Two Fractionation Schedules in Patients With Low-Risk Prostate Cancer.
J Clin Oncol. 2024 Jul 10;42(20):2377-2381.
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Capecitabine or Capecitabine Plus Oxaliplatin Versus Fluorouracil Plus Cisplatin in Definitive Concurrent Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma (CRTCOESC): A Multicenter, Randomized, Open-Label, Phase 3 Trial.
J Clin Oncol. 2024 Jul 10;42(20):2436-2445.
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LACC Trial: Final Analysis on Overall Survival Comparing Open Versus Minimally Invasive Radical Hysterectomy for Early-Stage Cervical Cancer.
J Clin Oncol. 2024 Aug 10;42(23):2741-2746.
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Osimertinib after Chemoradiotherapy in Stage III EGFR-Mutated NSCLC.
N Engl J Med. 2024 Aug 15;391(7):585-597.
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Long-Term Outcomes After Concurrent Once- or Twice-Daily Chemoradiation in Limited-Stage Small Cell Lung Cancer: A Brief Report From the CONVERT Trial.
Int J Radiat Oncol Biol Phys. 2024 Aug 1;119(5):1386-1390.
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Stereotactic radiotherapy vs whole brain radiation therapy in EGFR mutated NSCLC: Results & reflections from the prematurely closed phase III HYBRID trial.
Radiother Oncol. 2024 Aug;197:110334.
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Prostate high dose-rate brachytherapy as monotherapy for low and intermediate-risk prostate cancer: Efficacy results from a randomized phase II clinical trial of one fraction of 19 Gy or two fractions of 13.5 Gy: A 9-year update.
Radiother Oncol. 2024 Sep;198:110381.
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Recurrence of Non-Small Cell Lung Cancer With Visceral Pleural Invasion: A Secondary Analysis of a Randomized Clinical Trial.
JAMA Oncol. 2024 Sep 1;10(9):1179-1186.
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Diagnostic CT-Enabled Planning (DART): Results of a Randomized Trial in Palliative Radiation Therapy.
Int J Radiat Oncol Biol Phys. 2024 Sep 1;120(1):69-76.
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A Randomized Trial Comparing Quality of Life After Low-Dose Rate or High-Dose Rate Prostate Brachytherapy Boost With Pelvic External Beam Radiation Therapy.
Int J Radiat Oncol Biol Phys. 2024 Sep 1;120(1):59-68.
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Postoperative radiotherapy in women with early operable breast cancer (Scottish Breast Conservation Trial): 30-year update of a randomised, controlled, phase 3 trial.
Lancet Oncol. 2024 Sep;25(9):1213-1221.
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Late Urinary Toxicity and Quality of Life With Pelvic Radiation Therapy for High-Risk Prostate Cancer: Dose-Effect Relations in the POP-RT Randomized Phase 3 Trial.
Int J Radiat Oncol Biol Phys. 2024 Oct 1;120(2):537-543.
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Induction chemotherapy followed by standard chemoradiotherapy versus standard chemoradiotherapy alone in patients with locally advanced cervical cancer (GCIG INTERLACE): an international, multicentre, randomised phase 3 trial.
Lancet. 2024 Oct 19;404(10462):1525-1535.
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Pembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 trial.
Lancet. 2024 Oct 5;404(10460):1321-1332.
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Phase 3 Trial of Stereotactic Body Radiotherapy in Localized Prostate Cancer.
N Engl J Med. 2024 Oct 17;391(15):1413-1425.
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Durvalumab after Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer.
N Engl J Med. 2024 Oct 10;391(14):1313-1327.
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Palliative radiotherapy versus best supportive care in patients with painful hepatic cancer (CCTG HE1): a multicentre, open-label, randomised, controlled, phase 3 study.
Lancet Oncol. 2024 Oct;25(10):1337-1346.
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Comparison of liposomal gel with and without addition of chamomile for prevention of radiation dermatitis in head and neck cancer patients: A randomized controlled trial.
Radiother Oncol. 2024 Oct;199:110440.
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The significance of consolidation chemotherapy after concurrent chemoradiotherapy in esophageal squamous cell carcinoma: a randomized controlled phase III clinical trial.
Thorac Cancer. 2024 Oct;15(28):2038-2048.
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High-dose hyperfractionated simultaneous integrated boost radiotherapy versus standard-dose radiotherapy for limited-stage small-cell lung cancer in China: a multicentre, open-label, randomised, phase 3 trial.
Lancet Respir Med. 2024 Oct;12(10):799-809.
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Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiotherapy in patients with locally advanced rectal cancer: long-term results of the UNICANCER-PRODIGE 23 trial.
Ann Oncol. 2024 Oct;35(10):873-881.
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Conditional Risk and Predictive Factors Associated With Late Toxicity in Patients With Prostate Cancer Treated With External Beam Radiation Therapy Alone in the Randomized Trial RTOG 0126.
Int J Radiat Oncol Biol Phys. 2024 Nov 15;120(4):990-998.
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Application of Recombinant Human Superoxide Dismutase in Radical Concurrent Chemoradiotherapy for Cervical Cancer to Prevent and Treat Radiation-induced Acute Rectal Injury: A Multicenter, Randomized, Open-label, Prospective Trial.
Int J Radiat Oncol Biol Phys. 2024 Nov 1;120(3):720-729.
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Perioperative Durvalumab with Neoadjuvant Chemotherapy in Operable Bladder Cancer.
N Engl J Med. 2024 Nov 14;391(19):1773-1786.
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Preoperative Chemoradiotherapy for Resectable Gastric Cancer.
N Engl J Med. 2024 Nov 14;391(19):1810-1821.
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Efficacy and safety of prostate radiotherapy in de novo metastatic castration-sensitive prostate cancer (PEACE-1): a multicentre, open-label, randomised, phase 3 study with a 2 × 2 factorial design.
Lancet. 2024 Nov 23;404(10467):2065-2076.
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Post-hoc analysis of clinicopathological factors affecting lateral lymph node metastasis based on STELLAR study for rectal cancer.
Radiother Oncol. 2024 Nov;200:110512.
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Extent of Lymphadenectomy for Surgical Management of Right-Sided Colon Cancer: The Randomized Phase III RELARC Trial.
J Clin Oncol. 2024 Nov 20;42(33):3957-3966.
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Stereotactic vs Hypofractionated Radiotherapy for Inoperable Stage I Non-Small Cell Lung Cancer: The LUSTRE Phase 3 Randomized Clinical Trial.
JAMA Oncol. 2024 Nov;10(11):1571-1575.
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Randomised Trial of No, Short-term, or Long-term Androgen Deprivation Therapy with Postoperative Radiotherapy After Radical Prostatectomy: Results from the Three-way Comparison of RADICALS-HD (NCT00541047).
Eur Urol. 2024 Nov;86(5):422-430.
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Three-Dimensional Conformal Radiotherapy Versus Image-Guided Intensity Modulated External Beam Radiotherapy in Locally Advanced Cervical Cancer: A Phase III Randomized Control Study.
Clin Oncol (R Coll Radiol). 2024 Nov;36(11):728-737.
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ENGOT-en11/GOG-3053/KEYNOTE-B21: a randomised, double-blind, phase III study of pembrolizumab or placebo plus adjuvant chemotherapy with or without radiotherapy in patients with newly diagnosed, high-risk endometrial cancer.
Ann Oncol. 2024 Nov;35(11):968-980.
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Stereotactic Body Proton Therapy Versus Conventionally Fractionated Proton Therapy for Early Prostate Cancer: A Randomized, Controlled, Phase 3 Trial.
Int J Radiat Oncol Biol Phys. 2024 Dec 1;120(5):1377-1385.
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Helical Tomotherapy Versus 3-Dimensional Conformal Radiation Therapy in High-Risk Prostate Cancer: A Phase 3 Randomized Controlled Trial.
Int J Radiat Oncol Biol Phys. 2024 Dec 1;120(5):1386-1393.
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Prospective, Randomized Controlled Pivotal Trial of Biodegradable Balloon Rectal Spacer for Prostate Radiation Therapy.
Int J Radiat Oncol Biol Phys. 2003 Sep 1;57(1):166-71.
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Involved-site Radiation Therapy is Equally Effective and Less Toxic Than Involved-field Radiation Therapy in Patients Receiving Combined Modality Treatment for Early-stage Unfavorable Hodgkin Lymphoma-An Analysis of the Randomized Phase 3 HD17 Trial of the German Hodgkin Study Group.
Int J Radiat Oncol Biol Phys. 2024 Dec 1;120(5):1344-1352.
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Radiotherapy with cetuximab or durvalumab for locoregionally advanced head and neck cancer in patients with a contraindication to cisplatin (NRG-HN004): an open-label, multicentre, parallel-group, randomised, phase 2/3 trial.
Lancet Oncol. 2024 Dec;25(12):1576-1588.
Více informací ZDE
Radiotherapy Versus Transoral Robotic Surgery for Oropharyngeal Squamous Cell Carcinoma: Final Results of the ORATOR Randomized Trial.
J Clin Oncol. 2024 Dec;42(34):4023-4028.
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Omission of Radiotherapy in Primary Mediastinal B-Cell Lymphoma: IELSG37 Trial Results.
J Clin Oncol. 2024 Dec;42(34):4071-4083.
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Effect of Adding Electroacupuncture to Standard Triple Antiemetic Therapy on Chemotherapy-Induced Nausea and Vomiting: A Randomized Controlled Clinical Trial.
J Clin Oncol. 2024 Dec;42(34):4051-4059.
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Oral Cannabis Extract for Secondary Prevention of Chemotherapy-Induced Nausea and Vomiting: Final Results of a Randomized, Placebo-Controlled, Phase II/III Trial.
J Clin Oncol. 2024 Dec;42(34):4040-4050.
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Intra-prostatic recurrences after radiotherapy with focal boost: Location and dose mapping in the FLAME trial.
Radiother Oncol. 2024 Dec;201:110535.
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The EORTC 22922/10925 trial investigating regional nodal irradiation in stage I-III breast cancer: Outcomes according to locoregional and systemic therapies.
Radiother Oncol. 2024 Dec;201:110563.
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Breast induration and irradiated volume in the DBCG HYPO trial: The impact of age, smoking, and boost.
Radiother Oncol. 2024 Dec;201:110574.
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Radical Prostatectomy Versus Stereotactic Radiotherapy for Clinically Localised Prostate Cancer: Results of the PACE-A Randomised Trial.
Eur Urol. 2024 Dec;86(6):566-576.
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Osimertinib after definitive chemoradiotherapy in unresectable stage III epidermal growth factor receptor-mutated non-small-cell lung cancer: analyses of central nervous system efficacy and distant progression from the phase III LAURA study.
Ann Oncol. 2024 Dec;35(12):1116-1125.
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