Long-Term Follow-Up of the Response-Adapted Intergroup EORTC/LYSA/FIL H10 Trial for Localized Hodgkin Lymphoma.

J Clin Oncol. 2024 Jan 1;42(1):19-25.

Více informací ZDE 

Risk Modeling for Individualization of the FLAME Focal Boost Approach in External Beam Radiation Therapy for Patients With Localized Prostate Cancer.

Int J Radiat Oncol Biol Phys. 2024 Jan 1;118(1):66-73.

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Salivary Electrostimulation in the Treatment of Radiation Therapy-Induced Xerostomia (LEONIDAS-2): A Multicenter, Randomized, Double-Masked, Sham-Controlled, Phase 3 Trial.

Int J Radiat Oncol Biol Phys. 2024 Jan 1;118(1):142-153.

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Hypofractionated, Dose Escalation Radiation Therapy for High-Risk Prostate Cancer: The Safety Analysis of the Prostate Cancer Study-5, a Groupe de Radio-Oncologie Génito-Urinaire de Quebec Led Phase 3 Trial.

Int J Radiat Oncol Biol Phys. 2024 Jan 1;118(1):52-62.

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Simple versus Radical Hysterectomy in Women with Low-Risk Cervical Cancer.

N Engl J Med. 2024 Feb 29;390(9):819-829.

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Long-Term Results of Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy: The Randomized Phase II OPRA Trial.

J Clin Oncol. 2024 Feb 10;42(5):500-506.

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Severe Lymphopenia During Chemoradiation Therapy for Esophageal Cancer: Comprehensive Analysis of Randomized Phase 2B Trial of Proton Beam Therapy Versus Intensity Modulated Radiation Therapy.

Int J Radiat Oncol Biol Phys. 2024 Feb 1;118(2):368-377.

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Trimodality Therapy With Iodine-125 Brachytherapy, External Beam Radiation Therapy, and Short- or Long-Term Androgen Deprivation Therapy for High-Risk Localized Prostate Cancer: Results of a Multicenter, Randomized Phase 3 Trial (TRIP/TRIGU0907).

Int J Radiat Oncol Biol Phys. 2024 Feb 1;118(2):390-401.

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Whole-Brain Radiotherapy Alone vs Preceded by Bevacizumab, Etoposide, and Cisplatin for Untreated Brain Metastases From Breast Cancer: A Randomized Clinical Trial.

JAMA Oncol. 2024 Mar 1;10(3):325-334.

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Physician- and Patient-Reported Outcomes of the MC1635 Phase 3 Trial of Ultrahypofractionated Versus Moderately Hypofractionated Adjuvant Radiation Therapy After Breast-Conserving Surgery.

Int J Radiat Oncol Biol Phys. 2024 Mar 15;118(4):1049-1059.

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Dose-Intensified Postoperative Radiation Therapy for Prostate Cancer: Long-Term Results From the PKUFH Randomized Phase 3 Trial.

Int J Radiat Oncol Biol Phys. 2024 Mar 1;118(3):697-705.

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Intensity-Modulated Radiation Therapy Alone Versus Intensity-Modulated Radiation Therapy and Brachytherapy for Early-Stage Oropharyngeal Cancers: Results From a Randomized Controlled Trial.

Int J Radiat Oncol Biol Phys. 2024 Apr 1;118(5):1541-1551.

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Pembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): a randomised, double-blind, phase 3 clinical trial.

Lancet. 2024 Apr 6;403(10434):1341-1350.

Více informací ZDE 

Alectinib in Resected ALK-Positive Non-Small-Cell Lung Cancer.

N Engl J Med. 2024 Apr 11;390(14):1265-1276.

Více informací ZDE 

Omitting Axillary Dissection in Breast Cancer with Sentinel-Node Metastases.

N Engl J Med. 2024 Apr 4;390(13):1163-1175.

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Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma.

N Engl J Med. 2024 Apr 18;390(15):1359-1371.

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Streptococcus salivarius K12 Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors: A Randomized Controlled Trial.

J Clin Oncol. 2024 Apr 20;42(12):1426-1435.

Více informací ZDE 

Induction Chemotherapy Followed by Radiotherapy vs Chemoradiotherapy in Nasopharyngeal Carcinoma: A Randomized Clinical Trial.

JAMA Oncol. 2024 Apr 1;10(4):456-463.

Více informací ZDE 

Hyperbaric Oxygen Therapy and Late Local Toxic Effects in Patients With Irradiated Breast Cancer: A Randomized Clinical Trial.

JAMA Oncol. 2024 Apr 1;10(4):464-474.

Více informací ZDE 

Cost-effectiveness of weekly adaptive radiotherapy versus standard IMRT in head and neck cancer alongside the ARTIX trial.

Radiother Oncol. 2024 Apr;193:110116.

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Short course radiotherapy versus radiochemotherapy for locally advanced rectal cancers in the elderly (UNICANCER PRODIGE 42/GERICO 12 study): Quality of life and comprehensive geriatric assessment.

Radiother Oncol. 2024 Apr;193:110144.

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Tumor volume and cancer stem cell expression as prognostic markers for high-dose loco-regional failure in head and neck squamous cell carcinoma - A DAHANCA 19 study.

Radiother Oncol. 2024 Apr;193:110149.

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Moderate hypofractionated radiotherapy for prostate cancer: 3-year toxicity results of a multicentre randomized phase 3, non-inferiority trial.

Radiother Oncol. 2024 Apr;193:110089.

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Safety Analyses of the Phase 3 VISION Trial of [177Lu]Lu-PSMA-617 in Patients with Metastatic Castration-resistant Prostate Cancer.

Eur Urol. 2024 Apr;85(4):382-391.

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Effects of Androgen Deprivation Therapy on Prostate Cancer Outcomes According to Competing Event Risk: Secondary Analysis of a Phase 3 Randomised Trial.

Eur Urol. 2024 Apr;85(4):373-381.

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Noninferiority of Hypofractionated vs Conventional Postprostatectomy Radiotherapy for Genitourinary and Gastrointestinal Symptoms: The NRG-GU003 Phase 3 Randomized Clinical Trial.

JAMA Oncol. 2024 May 1;10(5):584-591.

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Late Toxicity of Prostate Ultrahypofractionated Radiation Therapy Compared With Moderate Hypofractionation in a Randomized Trial.

Int J Radiat Oncol Biol Phys. 2024 May 1;119(1):110-118.

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Timing of High-Dose-Rate Brachytherapy With External Beam Radiation Therapy in Patients With Intermediate- and High-Risk Localized Prostate Cancer and Its Effects on Toxicity and Quality of Life: A Randomized Controlled Trial (THEPCA).

Int J Radiat Oncol Biol Phys. 2024 May 1;119(1):90-99.

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Effect of Pelvic External Beam Radiation Therapy on Bone Mineral Density: A Secondary Analysis of a Phase 3 Randomized Controlled Trial.

Int J Radiat Oncol Biol Phys. 2024 May 1;119(1):119-126.

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Pembrolizumab Versus Placebo as Adjuvant Therapy in Resected Stage IIB or IIC Melanoma: Final Analysis of Distant Metastasis-Free Survival in the Phase III KEYNOTE-716 Study.

J Clin Oncol. 2024 May 10;42(14):1619-1624.

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Laparoscopic Versus Open Hemihepatectomy: The ORANGE II PLUS Multicenter Randomized Controlled Trial.

J Clin Oncol. 2024 May 20;42(15):1799-1809.

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Effectiveness of Endoscopic Screening on Esophageal Cancer Incidence and Mortality: A 9-Year Report of the Endoscopic Screening for Esophageal Cancer in China (ESECC) Randomized Trial.

J Clin Oncol. 2024 May 10;42(14):1655-1664.

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Pembrolizumab plus concurrent chemoradiotherapy versus placebo plus concurrent chemoradiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck (KEYNOTE-412): a randomised, double-blind, phase 3 trial.

Lancet Oncol. 2024 May;25(5):572-587.

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Perioperative Nivolumab in Resectable Lung Cancer.

N Engl J Med. 2024 May 16;390(19):1756-1769.

Více informací ZDE 

Improved Disease-Free Survival With Adjuvant Chemotherapy After Nephroureterectomy for Upper Tract Urothelial Cancer: Final Results of the POUT Trial.

J Clin Oncol. 2024 May 1;42(13):1466-1471.

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Induction-concurrent chemoradiotherapy with or without sintilimab in patients with locoregionally advanced nasopharyngeal carcinoma in China (CONTINUUM): a multicentre, open-label, parallel-group, randomised, controlled, phase 3 trial.

Lancet. 2024 Jun 22;403(10445):2720-2731.

Více informací ZDE 

Reduced-Volume Irradiation of Uninvolved Neck in Patients With Nasopharyngeal Cancer: Updated Results From an Open-Label, Noninferiority, Multicenter, Randomized Phase III Trial.

J Clin Oncol. 2024 Jun 10;42(17):2021-2025.

Více informací ZDE 

A multicentric randomized controlled phase III trial of adaptive and 18F-FDG-PET-guided dose-redistribution in locally advanced head and neck squamous cell carcinoma (ARTFORCE).

Radiother Oncol. 2024 Jul;196:110281.

Více informací ZDE 

Five-Year Mortality Outcomes for Eating As Treatment (EAT), a Health Behavior Change Intervention to Improve Nutrition in Patients With Head and Neck Cancer: A Stepped-Wedge, Randomized Controlled Trial.

Int J Radiat Oncol Biol Phys. 2024 Jul 15;119(4):1166-1170.

Více informací ZDE 

ESHO 1-85. Hyperthermia as an adjuvant to radiation therapy in the treatment of locally advanced breast carcinoma. A randomized multicenter study by the European Society for Hyperthermic Oncology.

Radiother Oncol. 2024 Jul;196:110313.

Více informací ZDE 

Radiation Therapy With or Without Cisplatin for Local Recurrences of Endometrial Cancer: Results From an NRG Oncology/GOG Prospective Randomized Multicenter Clinical Trial.

J Clin Oncol. 2024 Jul 10;42(20):2425-2435.

Více informací ZDE 

Image guided radiotherapy in curative treatment for prostate cancer. 5-year results from a randomized controlled trial (RIC-trial).

Radiother Oncol. 2024 Jul;196:110309.

Více informací ZDE 

Primary Surgery Followed by Selective Chemoradiotherapy Versus Preoperative Chemoradiotherapy Followed by Surgery for Locally Advanced Rectal Cancer: A Randomized Clinical Trial.

Int J Radiat Oncol Biol Phys. 2024 Jul 1;119(3):884-895.

Více informací ZDE 

Randomized Phase 3 Trial of the Hypoxia Modifier Nimorazole Added to Radiation Therapy With Benefit Assessed in Hypoxic Head and Neck Cancers Determined Using a Gene Signature (NIMRAD).

Int J Radiat Oncol Biol Phys. 2024 Jul 1;119(3):771-782.

Více informací ZDE 

Randomized self-controlled study comparing open-face vs. closed immobilization masks in fractionated cranial radiotherapy.

Radiother Oncol. 2024 Jul;196:110314.

Více informací ZDE 

Prostate-Specific Antigen Response to Androgen Deprivation Therapy in the Neoadjuvant Setting for High-Risk Prostate Adenocarcinoma (PIRANHA): Pooled Analysis of Two Randomized Clinical Trials.

Int J Radiat Oncol Biol Phys. 2024 Jul 1;119(3):826-831.

Více informací ZDE 

Impact of Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography on Prostate Cancer Salvage Radiotherapy Management: Results from a Prospective Multicenter Randomized Phase 3 Trial (PSMA-SRT NCT03582774).

Eur Urol. 2024 Jul;86(1):52-60.

Více informací ZDE 

Long-Term Quality-of-Life Outcomes After Prostate Radiation Therapy With or Without High-Dose-Rate Brachytherapy Boost: Post Hoc Analysis of TROG 03.04 RADAR.

Int J Radiat Oncol Biol Phys. 2024 Jul 1;119(3):813-825.

Více informací ZDE 

Long-Term Analysis of NRG Oncology RTOG 0415: A Randomized Phase III Noninferiority Study Comparing Two Fractionation Schedules in Patients With Low-Risk Prostate Cancer.

J Clin Oncol. 2024 Jul 10;42(20):2377-2381.

Více informací ZDE 

Capecitabine or Capecitabine Plus Oxaliplatin Versus Fluorouracil Plus Cisplatin in Definitive Concurrent Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma (CRTCOESC): A Multicenter, Randomized, Open-Label, Phase 3 Trial.

J Clin Oncol. 2024 Jul 10;42(20):2436-2445.

Více informací ZDE 

LACC Trial: Final Analysis on Overall Survival Comparing Open Versus Minimally Invasive Radical Hysterectomy for Early-Stage Cervical Cancer.

J Clin Oncol. 2024 Aug 10;42(23):2741-2746.

Více informací ZDE 

Osimertinib after Chemoradiotherapy in Stage III EGFR-Mutated NSCLC.

N Engl J Med. 2024 Aug 15;391(7):585-597.

Více informací ZDE 

Long-Term Outcomes After Concurrent Once- or Twice-Daily Chemoradiation in Limited-Stage Small Cell Lung Cancer: A Brief Report From the CONVERT Trial.

Int J Radiat Oncol Biol Phys. 2024 Aug 1;119(5):1386-1390.

Více informací ZDE 

Stereotactic radiotherapy vs whole brain radiation therapy in EGFR mutated NSCLC: Results & reflections from the prematurely closed phase III HYBRID trial.

Radiother Oncol. 2024 Aug;197:110334.

Více informací ZDE 

Prostate high dose-rate brachytherapy as monotherapy for low and intermediate-risk prostate cancer: Efficacy results from a randomized phase II clinical trial of one fraction of 19 Gy or two fractions of 13.5 Gy: A 9-year update.

Radiother Oncol. 2024 Sep;198:110381.

Více informací ZDE 

Recurrence of Non-Small Cell Lung Cancer With Visceral Pleural Invasion: A Secondary Analysis of a Randomized Clinical Trial.

JAMA Oncol. 2024 Sep 1;10(9):1179-1186.

Více informací ZDE 

Diagnostic CT-Enabled Planning (DART): Results of a Randomized Trial in Palliative Radiation Therapy.

Int J Radiat Oncol Biol Phys. 2024 Sep 1;120(1):69-76.

Více informací ZDE 

A Randomized Trial Comparing Quality of Life After Low-Dose Rate or High-Dose Rate Prostate Brachytherapy Boost With Pelvic External Beam Radiation Therapy.

Int J Radiat Oncol Biol Phys. 2024 Sep 1;120(1):59-68.

Více informací ZDE 

Postoperative radiotherapy in women with early operable breast cancer (Scottish Breast Conservation Trial): 30-year update of a randomised, controlled, phase 3 trial.

Lancet Oncol. 2024 Sep;25(9):1213-1221.

Více informací ZDE 

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