Randomizované studie 2017
Prognostic Factors for Local Control in Breast Cancer After Long-term Follow-up in the EORTC Boost vs No Boost Trial: A Randomized Clinical Trial.
JAMA Oncol. 2017 Jan 1;3(1):42-48.
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Prophylactic treatment with a potent corticosteroid cream ameliorates radiodermatitis, independent of radiation schedule: A randomized double blinded study.
Radiother Oncol. 2017 Jan;122(1):50-53.
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Does an integrated boost increase acute toxicity in prone hypofractionated breast irradiation? A randomized controlled trial.
Radiother Oncol. 2017 Jan;122(1):30-36.
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A randomised controlled trial of Caphosol mouthwash in management of radiation-induced mucositis in head and neck cancer.
Radiother Oncol. 2017 Feb;122(2):207-211.
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Reduction of the dose of radiotherapy to the elective neck in head and neck squamous cell carcinoma; a randomized clinical trial. Effect on late toxicity and tumor control.
Radiother Oncol. 2017 Feb;122(2):171-177.
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Long-Term Patient-Reported Outcomes From a Phase 3 Randomized Prospective Trial of Conventional Versus Hypofractionated Radiation Therapy for Localized Prostate Cancer.
Int J Radiat Oncol Biol Phys. 2017 Mar 15;97(4):722-731.
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Effect of Long-Term Hormonal Therapy (vs Short-Term Hormonal Therapy): A Secondary Analysis of Intermediate-Risk Prostate Cancer Patients Treated on NRG Oncology RTOG 9202.
Int J Radiat Oncol Biol Phys. 2017 Mar 1;97(3):511-515.
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Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Standard Radiation Versus Accelerated Radiation Plus Cisplatin for Locally Advanced Head and Neck Carcinoma: NRG Oncology RTOG 0129.
Int J Radiat Oncol Biol Phys. 2017 Mar 15;97(4):667-677.
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Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Accelerated Radiation Plus Cisplatin With or Without Cetuximab for Locally Advanced Head and Neck Carcinoma: NRG Oncology Radiation Therapy Oncology Group 0522.
Int J Radiat Oncol Biol Phys. 2017 Mar 15;97(4):687-699.
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Radiation with or without Antiandrogen Therapy in Recurrent Prostate Cancer.
N Engl J Med. 2017 Feb 2;376(5):417-428.
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Late side-effects and cosmetic results of accelerated partial breast irradiation with interstitial brachytherapy versus whole-breast irradiation after breast-conserving surgery for low-risk invasive and in-situ carcinoma of the female breast: 5-year results of a randomised, controlled, phase 3 trial.
Lancet Oncol. 2017 Feb;18(2):259-268.
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Best time to assess complete clinical response after chemoradiotherapy in squamous cell carcinoma of the anus (ACT II): a post-hoc analysis of randomised controlled phase 3 trial.
Lancet Oncol. 2017 Mar;18(3):347-356.
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Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma.
N Engl J Med. 2017 Mar 16;376(11):1027-1037.
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Optimal fractionation of preoperative radiotherapy and timing to surgery for rectal cancer (Stockholm III): a multicentre, randomised, non-blinded, phase 3, non-inferiority trial.
Lancet Oncol. 2017 Mar;18(3):336-346.
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Continued Benefit to Rectal Separation for Prostate Radiation Therapy: Final Results of a Phase III Trial.
Int J Radiat Oncol Biol Phys. 2017 Apr 1;97(5):976-985.
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The effect of post-mastectomy radiation in women with one to three positive nodes enrolled on the control arm of BCIRG-005 at ten year follow-up.
Radiother Oncol. 2017 Apr;123(1):10-14.
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Adjuvant chemotherapy in patients with locoregionally advanced nasopharyngeal carcinoma: Long-term results of a phase 3 multicentre randomised controlled trial.
Eur J Cancer. 2017 Apr;75:150-158.
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Eight-year follow up result of the OTOASOR trial: The Optimal Treatment Of the Axilla - Surgery Or Radiotherapy after positive sentinel lymph node biopsy in early-stage breast cancer: A randomized, single centre, phase III, non-inferiority trial.
Eur J Surg Oncol. 2017 Apr;43(4):672-679.
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Etoposide and cisplatin versus paclitaxel and carboplatin with concurrent thoracic radiotherapy in unresectable stage III non-small cell lung cancer: a multicenter randomized phase III trial.
Ann Oncol. 2017 Apr 1;28(4):777-783.
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Randomized study between radical surgery and radiotherapy for the treatment of stage IB-IIA cervical cancer: 20-year update.
J Gynecol Oncol. 2017 May;28(3):e34.
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Heart dose exposure as prognostic marker after radiotherapy for resectable stage IIIA/B non-small-cell lung cancer: secondary analysis of a randomized trial.
Ann Oncol. 2017 May 1;28(5):1084-1089.
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Accelerated partial breast irradiation using intensity modulated radiotherapy versus whole breast irradiation: Health-related quality of life final analysis from the Florence phase 3 trial.
Eur J Cancer. 2017 May;76:17-26.
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Dosimetric comparison between treatment plans of patients treated with low-dose-rate vs. high-dose-rate interstitial prostate brachytherapy as monotherapy: Initial findings of a randomized clinical trial.
Brachytherapy. 2017 May - Jun;16(3):608-615.
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Radiotherapy of painful heel spur with two fractionation regimens : Results of a randomized multicenter trial after 48 weeks follow-up.
Strahlenther Onkol. 2017 Jun;193(6):483-490.
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Moderate Hypofractionation in High-Risk, Organ-Confined Prostate Cancer: Final Results of a Phase III Randomized Trial.
J Clin Oncol. 2017 Jun 10;35(17):1891-1897.
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Androgen Suppression Combined with Elective Nodal and Dose Escalated Radiation Therapy (the ASCENDE-RT Trial): An Analysis of Survival Endpoints for a Randomized Trial Comparing a Low-Dose-Rate Brachytherapy Boost to a Dose-Escalated External Beam Boost for High- and Intermediate-risk Prostate Cancer.
Int J Radiat Oncol Biol Phys. 2017 Jun 1;98(2):275-285.
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ASCENDE-RT: An Analysis of Treatment-Related Morbidity for a Randomized Trial Comparing a Low-Dose-Rate Brachytherapy Boost with a Dose-Escalated External Beam Boost for High- and Intermediate-Risk Prostate Cancer.
Int J Radiat Oncol Biol Phys. 2017 Jun 1;98(2):286-295.
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Duration of Androgen Deprivation in Locally Advanced Prostate Cancer: Long-Term Update of NRG Oncology RTOG 9202.
Int J Radiat Oncol Biol Phys. 2017 Jun 1;98(2):296-303.
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Early Positron Emission Tomography Response-Adapted Treatment in Stage I and II Hodgkin Lymphoma: Final Results of the Randomized EORTC/LYSA/FIL H10 Trial.
J Clin Oncol. 2017 Jun 1;35(16):1786-1794.
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Randomized Trial of a Hypofractionated Radiation Regimen for the Treatment of Localized Prostate Cancer.
J Clin Oncol. 2017 Jun 10;35(17):1884-1890.
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Prophylactic cranial irradiation versus observation in patients with extensive-disease small-cell lung cancer: a multicentre, randomised, open-label, phase 3 trial.
Lancet Oncol. 2017 May;18(5):663-671.
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Long-Term Follow-Up of Contemporary Treatment in Early-Stage Hodgkin Lymphoma: Updated Analyses of the German Hodgkin Study Group HD7, HD8, HD10, and HD11 Trials.
J Clin Oncol. 2017 Jun 20;35(18):1999-2007.
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Survival Outcomes With Short-Course Radiation Therapy in Elderly Patients With Glioblastoma: Data From a Randomized Phase 3 Trial.
Int J Radiat Oncol Biol Phys. 2017 Jul 15;98(4):931-938.
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ASCENDE-RT: An Analysis of Health-Related Quality of Life for a Randomized Trial Comparing Low-Dose-Rate Brachytherapy Boost With Dose-Escalated External Beam Boost for High- and Intermediate-Risk Prostate Cancer.
Int J Radiat Oncol Biol Phys. 2017 Jul 1;98(3):581-589.
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Organ preservation for rectal cancer (GRECCAR 2): a prospective, randomised, open-label, multicentre, phase 3 trial.
Lancet. 2017 Jul 29;390(10093):469-479.
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Final Report of a Prospective Randomized Trial to Evaluate the Dose-Response Relationship for Postoperative RadiationTherapy and Pathologic Risk Groups in Patients With Head and Neck Cancer.
Int J Radiat Oncol Biol Phys. 2017 Aug 1;98(5):1002-1011.
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Concurrent once-daily versus twice-daily chemoradiotherapy in patients with limited-stage small-cell lung cancer (CONVERT): an open-label, phase 3, randomised, superiority trial.
Lancet Oncol. 2017 Aug;18(8):1116-1125 .
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Post-operative stereotactic radiosurgery versus observation for completely resected brain metastases: a single-centre, randomised, controlled, phase 3 trial.
Lancet Oncol. 2017 Aug;18(8):1040-1048.
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Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C/CEC•3): a multicentre, randomised, controlled, phase 3 trial.
Lancet Oncol. 2017 Aug;18(8):1049-1060.
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Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial.
Lancet. 2017 Sep 9;390(10099):1048-1060.
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Long-Term Results of a Randomized Trial Comparing Iridium Implant Plus External Beam Radiation Therapy With External Beam Radiation Therapy Alone in Node-Negative Locally Advanced Cancer of the Prostate.
Int J Radiat Oncol Biol Phys. 2017 Sep 1;99(1):90-93.
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Preoperative chemotherapy versus chemoradiotherapy in locally advanced adenocarcinomas of the oesophagogastric junction (POET): Long-term results of a controlled randomised trial.
Eur J Cancer. 2017 Aug;81:183-190.
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First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials.
Lancet Oncol. 2017 Sep;18(9):1159-1171.
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Induction TPF followed by concomitant treatment versus concomitant treatment alone in locally advanced head and neck cancer. A phase II-III trial.
Ann Oncol. 2017 Sep 1;28(9):2206-2212.
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Prospective, Randomized Study of Radiation Dose Escalation With Combined Proton-Photon Therapy for Benign Meningiomas.
Int J Radiat Oncol Biol Phys. 2017 Nov 15;99(4):787-796.
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Multicenter Randomized Double-Blind, Placebo-Controlled Trial GORTEC (Groupe Oncologie Radiotherapie Tete et Cou) 2009-01 Evaluating the Effect of the Regenerating Agent on Radiodermatitis of Head and Neck Cancer Patients.
Int J Radiat Oncol Biol Phys. 2017 Nov 1;99(3):590-595.
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Effect of Breast Irradiation on Cardiac Disease in Women Enrolled in BCIRG-001 at 10-Year Follow-Up.
Int J Radiat Oncol Biol Phys. 2017 Nov 1;99(3):541-548.
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Adjuvant Chemoradiotherapy With Epirubicin, Cisplatin, and Fluorouracil Compared With Adjuvant Chemoradiotherapy With Fluorouracil and Leucovorin After Curative Resection of Gastric Cancer: Results From CALGB 80101 (Alliance).
J Clin Oncol. 2017 Nov 10;35(32):3671-3677.
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A multicenter, phase 3, randomized trial of concurrent chemoradiotherapy plus adjuvant chemotherapy versus radiotherapy alone in patients with regionally advanced nasopharyngeal carcinoma: 10-year outcomes for efficacy and toxicity.
Cancer. 2017 Nov 1;123(21):4147-4157.
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Stereotactic Radiosurgery With or Without Whole-Brain Radiation Therapy for Limited Brain Metastases: A Secondary Analysis of the North Central Cancer Treatment Group N0574 (Alliance) Randomized Controlled Trial.
Int J Radiat Oncol Biol Phys. 2017 Dec 1;99(5):1173-1178.
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Efficacy and safety of selective internal radiotherapy with yttrium-90 resin microspheres compared with sorafenib in locally advanced and inoperable hepatocellular carcinoma (SARAH): an open-label randomised controlled phase 3 trial.
Lancet Oncol. 2017 Dec;18(12):1624-1636.
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Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma: A Randomized Clinical Trial.
JAMA. 2017 Dec 19;318(23):2306-2316.
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