Randomizované studie 2010
Radiation therapy and tamoxifen after breast-conserving surgery: updated results of a 2 x 2 randomised clinical trial in patients with low risk of recurrence.
Eur J Cancer. 2010 Jan;46(1):95-101.
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Is biochemical response more important than duration of neoadjuvant hormone therapy before radiotherapy for clinically localized prostate cancer? An analysis of the 3- versus 8-month randomized trial.
Int J Radiat Oncol Biol Phys. 2010 Jan 1;76(1):23-30.
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A Prospective Phase III Randomized Trial of Hypofractionation Versus Conventional Fractionation in Patients with High-Risk Prostate Cancer.
Int J Radiat Oncol Biol Phys. 2010 Jan 2. [Epub ahead of print].
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Dose–Volume Constraints to Reduce Rectal Side Effects From Prostate Radiotherapy: Evidence From MRC RT01 Trial ISRCTN 47772397 .
Int J Radiat Oncol Biol Phys. Volume 76, Issue 3, 1 March 2010, Pages 747-754.
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Randomized Trial Comparing Conventional-Dose With High-Dose Conformal Radiation Therapy in Early-Stage Adenocarcinoma of the Prostate: Long-Term Results From Proton Radiation Oncology Group/American College of Radiology 95-09.
J Clin Oncol. 2010 Feb 1. [Epub ahead of print].
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Cone-beam CT assessment of interfraction and intrafraction setup error of two head-and-neck cancer thermoplastic masks.
Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3):949-55. Epub 2010 Jan 7.
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A prospective randomized trial to study the impact of pretreatment FDG-PET for cervical cancer patients with MRI-detected positive pelvic but negative para-aortic lymphadenopathy.
Int J Radiat Oncol Biol Phys. 2010 Feb 1;76(2):477-84. Epub 2009 May 21.
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A randomized phase III study of adjuvant platinum/docetaxel chemotherapy with or without radiation therapy in patients with gastric cancer.
Cancer Chemother Pharmacol. 2010 Feb 4. [Epub ahead of print].
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Comparison of patient-reported breast, arm, and shoulder symptoms and body image after radiotherapy for early breast cancer: 5-year follow-up in the randomised Standardisation of Breast Radiotherapy (START) trials.
The Lancet Oncology, Volume 11, Issue 3, Pages 231 - 240, March 2010.
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Concurrent or sequential adjuvant letrozole and radiotherapy after conservative surgery for early-stage breast cancer (CO-HO-RT): a phase 2 randomised trial.
The Lancet Oncology, Volume 11, Issue 3, Pages 258 - 265, March 2010.
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Intra-arterial versus intravenous chemoradiation for advanced head and neck cancer: Results of a randomized phase 3 trial.
Cancer. 2010 Feb 24. [Epub ahead of print].
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Long-term results of hypofractionated radiation therapy for breast cancer.
N Engl J Med. 2010 Feb 11;362(6):513-20.
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Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial.
Lancet. 2010 Mar 6;375(9717):816-23.
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Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I).
Br J Cancer. 2010 Mar 30;102(7):1123-8. Epub 2010 Mar 16.
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Toxicity at three years with and without irradiation of the internal mammary and medial supraclavicular lymph node chain in stage I to III breast cancer (EORTC trial 22922/10925).
Acta Oncol. 2010;49(1):24-34.
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Octreotide acetate in prevention of chemoradiation-induced diarrhea in anorectal cancer: randomized RTOG trial 0315.
J Natl Cancer Inst. 2010 Apr 21;102(8):547-56. Epub 2010 Mar 25.
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Impact of high-dose chemotherapy on the ability to deliver subsequent local-regional radiotherapy for breast cancer: analysis of Cancer and Leukemia Group B Protocol 9082.
Int J Radiat Oncol Biol Phys. 2010 Apr;76(5):1305-13. Epub 2009 Sep 9.
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Neoadjuvant LHRH analog plus estramustine phosphate combined with three-dimensional conformal radiotherapy for intermediate- to high-risk prostate cancer: a randomized study.
Int Urol Nephrol. 2010 Mar;42(1):81-8. Epub 2009 May 16.
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Sentinel lymph node biopsy in breast cancer: ten-year results of a randomized controlled study.
Ann Surg. 2010 Apr;251(4):595-600.
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Dose Escalation and Quality of Life in Patients with Localized Prostate Cancer Treated with Radiotherapy: Long-Term Results of the Dutch Randomized Dose-Escalation Trial (CKTO 96-10 Trial).
Int J Radiat Oncol Biol Phys. 2010 Apr 24. [Epub ahead of print].
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Five versus six fractions of radiotherapy per week for squamous-cell carcinoma of the head and neck (IAEA-ACC study): a randomised, multicentre trial.
Lancet Oncol. 2010 Apr 8. [Epub ahead of print].
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Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2.
J Clin Oncol. 2010 Apr 1;28(10):1638-44. Epub 2010 Mar 1.
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Mature results of a randomized trial of accelerated hyperfractionated versus conventional radiotherapy in head-and-neck cancer.
Int J Radiat Oncol Biol Phys. 2010 May 1;77(1):3-8.
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Randomized phase III trial comparing induction chemotherapy followed by radiotherapy to concomitant chemoradiotherapy for laryngeal preservation in T3M0 pyriform sinus carcinoma.
Acta Otolaryngol. 2010;130(1):150-5.
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Acute and Late Toxicity in a Randomized Trial of Conventional Versus Hypofractionated Three-Dimensional Conformal Radiotherapy for Prostate Cancer.
Int J Radiat Oncol Biol Phys. 2010 May 5. [Epub ahead of print].
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Tirapazamine, cisplatin, and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck (TROG 02.02, HeadSTART): a phase III trial of the Trans-Tasman Radiation Oncology Group.
J Clin Oncol. 2010 Jun 20;28(18):2989-95. Epub 2010 May 17.
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Predicting the effect of accelerated fractionation in postoperative radiotherapy for head and neck cancer based on molecular marker profiles: data from a randomized clinical trial.
Int J Radiat Oncol Biol Phys. 2010 Jun 1;77(2):438-46. Epub 2009 Sep 3.
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A phase III randomized trial of the timing of meloxicam with iodine-125 prostate brachytherapy.
Int J Radiat Oncol Biol Phys. 2010 Jun 1;77(2):496-501. Epub 2010 Mar 28.
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Accelerated partial breast irradiation with IMRT: new technical approach and interim analysis of acute toxicity in a phase III randomized clinical trial.
Int J Radiat Oncol Biol Phys. 2010 Jun 1;77(2):509-15. Epub 2009 Aug 21.
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Randomized Trial of Radiotherapy Plus Concurrent-Adjuvant Chemotherapy vs Radiotherapy Alone for Regionally Advanced Nasopharyngeal Carcinoma.
J Natl Cancer Inst. 2010 Aug 4;102(15):1188-98. Epub 2010 Jul 15.
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Impact of Short-Course Preoperative Radiotherapy for Rectal Cancer on Patients' Quality of Life: Data From the Medical Research Council CR07/National Cancer Institute of Canada Clinical Trials Group C016 Randomized Clinical Trial.
J Clin Oncol. 2010 Jun 28. [Epub ahead of print].
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Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial.
Lancet. 2010 Jul 10;376(9735):91-102.
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Subgroup analysis of patients with localized prostate cancer treated within the Dutch-randomized dose escalation trial.
Radiother Oncol. 2010 Jul;96(1):13-8. Epub 2010 Mar 11.
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Consolidation radiotherapy in patients with advanced Hodgkin's lymphoma: survival data from the UKLG LY09 randomized controlled trial (ISRCTN97144519).
J Clin Oncol. 2010 Jul 10;28(20):3352-9. Epub 2010 May 24.
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Cognition and quality of life after chemotherapy plus radiotherapy (RT) vs. RT for pure and mixed anaplastic oligodendrogliomas: radiation therapy oncology group trial 9402.
Int J Radiat Oncol Biol Phys. 2010 Jul 1;77(3):662-9. Epub 2009 Sep 23.
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Late gastrointestinal toxicity after dose-escalated conformal radiotherapy for early prostate cancer: results from the UK Medical Research Council RT01 trial (ISRCTN47772397).
Int J Radiat Oncol Biol Phys. 2010 Jul 1;77(3):773-83. Epub 2009 Oct 14.
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Randomized comparison of whole brain radiotherapy, 20 Gy in four daily fractions versus 40 Gy in 20 twice-daily fractions, for brain metastases.
Int J Radiat Oncol Biol Phys. 2010 Jul 1;77(3):648-54. Epub 2009 Oct 14.
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Radiation with or without 6 months of androgen suppression therapy in intermediate- and high-risk clinically localized prostate cancer: a postrandomization analysis by risk group.
Int J Radiat Oncol Biol Phys. 2010 Jul 15;77(4):1046-52. Epub 2009 Oct 26.
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Long-Term Results of a Randomized Trial on the Sequencing of Radiotherapy and Chemotherapy in Breast Cancer.
Am J Clin Oncol. 2010 Aug 27. [Epub ahead of print].
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Mometasone Furoate Effect on Acute Skin Toxicity in Breast Cancer Patients Receiving Radiotherapy: A Phase III Double-Blind, Randomized Trial from the North Central Cancer Treatment Group N06C4.
Int J Radiat Oncol Biol Phys. 2010 Aug 26. [Epub ahead of print].
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Late Patient-Reported Toxicity After Preoperative Radiotherapy or Chemoradiotherapy in Nonresectable Rectal Cancer: Results From a Randomized Phase III Study.
Int J Radiat Oncol Biol Phys. 2010 Oct 5. [Epub ahead of print].
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Hypofractionated Versus Conventionally Fractionated Radiotherapy for Prostate Carcinoma: Final Results of Phase III Randomized Trial.
Int J Radiat Oncol Biol Phys. 2010 Oct 7. [Epub ahead of print].
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External irradiation with or without long-term androgen suppression for prostate cancer with high metastatic risk: 10-year results of an EORTC randomised study.
Lancet Oncol. 2010 Nov;11(11):1066-73. Epub 2010 Oct 7.
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Early versus delayed treatment of relapsed ovarian cancer (MRC OV05/EORTC 55955): a randomised trial.
Lancet. 2010 Oct 2;376(9747):1155-63.
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Adding external beam to intra-luminal brachytherapy improves palliation in obstructive squamous cell oesophageal cancer: A prospective multi-centre randomized trial of the International Atomic Energy Agency.
Radiother Oncol. 2010 Oct 13. [Epub ahead of print].
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A randomized trial on addition of concurrent-adjuvant chemotherapy and/or accelerated fractionation for locally-advanced nasopharyngeal carcinoma.
Radiother Oncol. 2010 Oct 22. [Epub ahead of print].
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Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial.
Lancet Oncol. 2010 Oct;11(10):927-33.
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Randomized Trial of Postoperative Adjuvant Therapy in Stage II and III Rectal Cancer to Define the Optimal Sequence of Chemotherapy and Radiotherapy: 10-Year Follow-Up.
Int J Radiat Oncol Biol Phys. 2010 Oct 5. [Epub ahead of print].
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The importance of haemoglobin level and effect of transfusion in HNSCC patients treated with radiotherapy - Results from the randomized DAHANCA 5 study.
Radiother Oncol. 2010 Oct 20. [Epub ahead of print].
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A prospective phase III randomized trial of hypofractionation versus conventional fractionation in patients with high-risk prostate cancer.
Int J Radiat Oncol Biol Phys. 2010 Sep 1;78(1):11-8. Epub 2010 Jan 4.
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Impact of short-course preoperative radiotherapy for rectal cancer on patients' quality of life: data from the Medical Research Council CR07/National Cancer Institute of Canada Clinical Trials Group C016 randomized clinical trial.
J Clin Oncol. 2010 Sep 20;28(27):4233-9. Epub 2010 Jun 28.
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Phase III Study of Radiation Therapy With or Without Cis-Platinum in Patients with Unresectable Squamous or Undifferentiated Carcinoma of the Head and Neck: An Intergroup Trial of the Eastern Cooperative Oncology Group (E2382).
Int J Radiat Oncol Biol Phys. 2010 Sep 30. [Epub ahead of print].
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Palliative Stenting With or Without Radiotherapy for Inoperable Esophageal Carcinoma: A Randomized Trial.
J Gastrointest Cancer. 2010 Sep 14. [Epub ahead of print].
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High-dose methotrexate with or without whole brain radiotherapy for primary CNS lymphoma (G-PCNSL-SG-1): a phase 3, randomised, non-inferiority trial.
Lancet Oncol. 2010 Nov;11(11):1036-47. Epub 2010 Oct 20.
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Radiotherapy followed by adjuvant temozolomide with or without neoadjuvant ACNU-CDDP chemotherapy in newly diagnosed glioblastomas: a prospective randomized controlled multicenter phase III trial.
J Neurooncol. 2010 Nov 4. [Epub ahead of print].
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Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology.
Int J Radiat Oncol Biol Phys. 2010 Nov 1;78(3):828-35. Epub 2010 Feb 3.
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Symptoms 10-17 years after breast cancer radiotherapy data from the randomised SWEBCG91-RT trial.
Radiother Oncol 2010 Nov;97(2):281-7. Epub 2010 Oct 20.
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Radiotherapy with concurrent carbogen and nicotinamide in bladder carcinoma.
J Clin Oncol. 2010 Nov 20;28(33):4912-8. Epub 2010 Oct 18.
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70 Gy Versus 80 Gy in Localized Prostate Cancer: 5-Year Results of GETUG 06 Randomized Trial.
Int J Radiat Oncol Biol Phys. 2010 Dec 11. [Epub ahead of print].
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A randomised trial of Supine versus Prone breast radiotherapy (SuPr study): Comparing set-up errors and respiratory motion.
Radiother Oncol. 2010 Dec 13. [Epub ahead of print].
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Oral Mucositis Prevention by Low-Level Laser Therapy in Head-and-Neck Cancer Patients Undergoing Concurrent Chemoradiotherapy: A Phase III Randomized Study.
Int J Radiat Oncol Biol Phys. 2010 Dec 14. [Epub ahead of print].
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Timing of salvage hormonal therapy in prostate cancer patients with unfavorable prognosis treated with radiotherapy: a secondary analysis of Radiation Therapy Oncology Group 85-31.
Int J Radiat Oncol Biol Phys. 2010 Dec 1;78(5):1301-6. Epub 2010 Mar 29.
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