Randomizované studie 2012
Oral mucositis prevention by low-level laser therapy in head-and-neck cancer patients undergoing concurrent chemoradiotherapy: a phase III randomized study.
Int J Radiat Oncol Biol Phys. 2012 Jan 1;82(1):270-5.
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Adjuvant chemoradiotherapy with or without intraoperative radiotherapy for the treatment of resectable locally advanced gastric adenocarcinoma.
Radiother Oncol. 2012 Jan;102(1):51-5.
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Randomized controlled trial of forward-planned intensity modulated radiotherapy for early breast cancer: interim results at 2 years.
Int J Radiat Oncol Biol Phys. 2012 Feb 1;82(2):715-23.
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Failure to adhere to protocol specified radiation therapy guidelines was associated with decreased survival in RTOG 9704-a phase III trial of adjuvant chemotherapy and chemoradiotherapy for patients with resected adenocarcinoma of the pancreas.
Int J Radiat Oncol Biol Phys. 2012 Feb 1;82(2):809-16.
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Concomitant chemoradiotherapy versus acceleration of radiotherapy with or without concomitant chemotherapy in locally advanced head and neck carcinoma (GORTEC 99-02): an open-label phase 3 randomised trial.
Lancet Oncol. 2012 Feb;13(2):145-53.
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20 Gy versus 44 Gy of supplemental external beam radiotherapy with palladium-103 for patients with greater risk disease: results of a prospective randomized trial.
Int J Radiat Oncol Biol Phys. 2012 Mar 1;82(3):e449-55.
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Radiotherapy with or without chemotherapy in muscle-invasive bladder cancer.
N Engl J Med. 2012 Apr 19;366(16):1477-88.
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Prevalence and peak incidence of acute and late normal tissue morbidity in the DAHANCA 6&7 randomised trial with accelerated radiotherapy for head and neck cancer.
Radiother Oncol. 2012 Apr;103(1):69-75.
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Randomised trial of external beam radiotherapy alone or combined with high-dose-rate brachytherapy boost for localised prostate cancer.
Radiother Oncol. 2012 May;103(2):217-22.
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Accelerated Radiotherapy With Carbogen and Nicotinamide for Laryngeal Cancer: Results of a Phase III Randomized Trial.
J Clin Oncol. 2012 May 20;30(15):1777-83.
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Preoperative chemoradiotherapy for esophageal or junctional cancer.
N Engl J Med. 2012 May 31;366(22):2074-84.
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Effects of a dietary intervention on acute gastrointestinal side effects and other aspects of health-related quality of life: A randomized controlled trial in prostate cancer patients undergoing radiotherapy.
Radiother Oncol. 2012 Jun;103(3):333-40.
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Correlation in rectal cancer between clinical tumor response after neoadjuvant radiotherapy and sphincter or organ preservation: 10-year results of the lyon R 96-02 randomized trial.
Int J Radiat Oncol Biol Phys. 2012 Jun 1;83(2):e165-71.
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Preoperative Versus Postoperative Chemoradiotherapy for Locally Advanced Rectal Cancer: Results of the German CAO/ARO/AIO-94 Randomized Phase III Trial After a Median Follow-Up of 11 Years.
J Clin Oncol. 2012 Jun 1;30(16):1926-33..
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Induction chemotherapy and dose intensification of the radiation boost in locally advanced anal canal carcinoma: final analysis of the randomized UNICANCER ACCORD 03 trial.
J Clin Oncol. 2012 Jun 1;30(16):1941-8.
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Adjuvant radiotherapy versus observation alone for patients at risk of lymph-node field relapse after therapeutic lymphadenectomy for melanoma: a randomised trial.
Lancet Oncol. 2012 Jun;13(6):589-97.
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Randomized clinical trial to assess the efficacy of radiotherapy in primary mediastinal large B-lymphoma.
Int J Radiat Oncol Biol Phys. 2012 Jul 15;83(4):1227-31.
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Topical hyaluronic acid vs. standard of care for the prevention of radiation dermatitis after adjuvant radiotherapy for breast cancer: single-blind randomized phase III clinical trial.
Int J Radiat Oncol Biol Phys. 2012 Jul 15;83(4):1089-94.
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Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial.
Lancet Oncol. 2012 Jul;13(7):707-15.
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Updated analysis of SWOG-directed intergroup study 0116: a phase III trial of adjuvant radiochemotherapy versus observation after curative gastric cancer resection.
J Clin Oncol. 2012 Jul 1;30(19):2327-33.
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Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial.
Lancet Oncol. 2012 Jul;13(7):679-87.
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Late radiation toxicity after intraoperative radiotherapy (IORT) for breast cancer: results from the randomized phase III trial TARGIT A.
Breast Cancer Res Treat. 2012 Aug;135(1):253-60.
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Predictors of severe late radiotherapy-related toxicity after hyperfractionated radiotherapy with or without concomitant cisplatin in locally advanced head and neck cancer. Secondary retrospective analysis of a randomized phase III trial (SAKK 10/94).
Radiother Oncol. 2012 Aug;104(2):213-218.
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External Pelvic and Vaginal Irradiation Versus Vaginal Irradiation Alone as Postoperative Therapy in Medium-Risk Endometrial Carcinoma: A Prospective, Randomized Study-Quality-of-Life Analysis.
Int J Gynecol Cancer. 2012 Sep;22(7):1281-8.
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Intermittent androgen suppression for rising PSA level after radiotherapy.
N Engl J Med. 2012 Sep 6;367(10):895-903.
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Extended followup oncologic outcome of randomized trial between cryoablation and external beam therapy for locally advanced prostate cancer (t2c-t3b).
J Urol. 2012 Oct;188(4):1170-5.
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Benign painful elbow syndrome : First results of a single center prospective randomized radiotherapy dose optimization trial.
Strahlenther Onkol. 2012 Oct;188(10):873-877.
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A randomized, controlled, multicenter study comparing intensity-modulated radiotherapy plus concurrent chemotherapy with chemotherapy alone in gastric cancer patients with D2 resection.
Radiother Oncol. 2012 Sep;104(3):361-6.
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Low level laser therapy for concurrent chemoradiotherapy induced oral mucositis in head and neck cancer patients - A triple blinded randomized controlled trial.
Radiother Oncol. 2012 Sep;104(3):349-54.
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The effect of short term neo-adjuvant androgen deprivation on erectile function in patients treated with external beam radiotherapy for localised prostate cancer: an analysis of the 4- versus 8-month randomised trial (Irish Clinical Oncology Research Group 97-01).
Radiother Oncol. 2012 Jul;104(1):96-102.
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Three-dimensional conformal radiotherapy (3D-CRT) versus intensity modulated radiation therapy (IMRT) in squamous cell carcinoma of the head and neck: A randomized controlled trial.
Radiother Oncol. 2012 Sep;104(3):343-8.
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A prospective, randomized study comparing outcomes and toxicities of intensity-modulated radiotherapy vs. conventional two-dimensional radiotherapy for the treatment of nasopharyngeal carcinoma.
Radiother Oncol. 2012 Sep;104(3):286-93.
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Radical radiotherapy with or without gemcitabine in patients with early stage medically inoperable non-small cell lung cancer.
Lung Cancer. 2012 Sep;77(3):532-6.
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Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial.
Lancet Oncol. 2012 Sep;13(9):916-26.
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Does preoperative radiotherapy with postoperative chemotherapy increase acute side-effects and postoperative complications of total mesorectal excision? Report of the randomized finnish rectal cancer trial.
Scand J Surg. 2012;101(4):275-82.
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Rectal and urinary dysfunction in the TROG 03.04 RADAR trial for locally advanced prostate cancer.
Radiother Oncol. 2012 Nov;105(2):184-92.
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Dose-effect relationship in chemoradiotherapy for locally advanced rectal cancer: a randomized trial comparing two radiation doses.
Int J Radiat Oncol Biol Phys. 2012 Nov 15;84(4):949-54.
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Open-label, multicenter, randomized phase III trial of adjuvant chemoradiation plus interferon Alfa-2b versus fluorouracil and folinic acid for patients with resected pancreatic adenocarcinoma.
J Clin Oncol. 2012 Nov 20;30(33):4077-83.
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Randomized, multicenter trial on the effect of radiation therapy on plantar fasciitis (painful heel spur) comparing a standard dose with a very low dose: mature results after 12 months' follow-up.
Int J Radiat Oncol Biol Phys. 2012 Nov 15;84(4):e455-62.
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Phase 3 trial of postoperative chemotherapy alone versus chemoradiation therapy in stage III-IV gastric cancer treated with R0 gastrectomy and D2 lymph node dissection.
Int J Radiat Oncol Biol Phys. 2012 Dec 1;84(5):e585-92.
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Long-Term Update of US GI Intergroup RTOG 98-11 Phase III Trial for Anal Carcinoma: Survival, Relapse, and Colostomy Failure With Concurrent Chemoradiation Involving Fluorouracil/Mitomycin Versus Fluorouracil/Cisplatin.
J Clin Oncol. 2012 Dec 10;30(35):4344-51.
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Postoperative radiotherapy after radical prostatectomy for high-risk prostate cancer: long-term results of a randomised controlled trial (EORTC trial 22911).
Lancet. 2012 Dec 8;380(9858):2018-27.
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Updated results and patterns of failure in a randomized hypofractionation trial for high-risk prostate cancer.
Int J Radiat Oncol Biol Phys. 2012 Dec 1;84(5):1172-8.
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