Randomizované studie 2011
Radiotherapy Breast Boost with Reduced Whole-Breast Dose is Associated with Improved Cosmesis: The Results of a Comprehensive Assessment from the St. George and Wollongong Randomized Breast Boost Trial.
Int J Radiat Oncol Biol Phys. 2011 Jan 19. [Epub ahead of print].
Více informací ZDE
Randomized Trial of Carboplatin Versus Radiotherapy for Stage I Seminoma: Mature Results on Relapse and Contralateral Testis Cancer Rates in MRC TE19/EORTC 30982 Study (ISRCTN27163214).
J Clin Oncol. 2011 Jan 31. [Epub ahead of print].
Více informací ZDE
A comparison of the prognostic value of early PSA test-based variables following external beam radiotherapy, with or without preceding androgen deprivation: analysis of data from the TROG 96.01 randomized trial.
Int J Radiat Oncol Biol Phys. 2011 Feb 1;79(2):385-91. Epub 2010 Mar 28.
Více informací ZDE
Subcutaneous compared with intravenous administration of amifostine in patients with head and neck cancer receiving radiotherapy: final results of the GORTEC2000-02 phase III randomized trial.
J Clin Oncol. 2011 Jan 10;29(2):127-33. Epub 2010 Nov 29.
Více informací ZDE
Effect of tamoxifen and radiotherapy in women with locally excised ductal carcinoma in situ: long-term results from the UK/ANZ DCIS trial.
Lancet Oncol. 2011 Jan;12(1):21-9. Epub 2010 Dec 7.
Více informací ZDE
Phase III comparison of prophylactic cranial irradiation versus observation in patients with locally advanced non-small-cell lung cancer: primary analysis of radiation therapy oncology group study RTOG 0214.
J Clin Oncol. 2011 Jan 20;29(3):272-8. Epub 2010 Dec 6.
Více informací ZDE
Phase III trial of prophylactic cranial irradiation compared with observation in patients with locally advanced non-small-cell lung cancer: neurocognitive and quality-of-life analysis.
J Clin Oncol. 2011 Jan 20;29(3):279-86. Epub 2010 Dec 6.
Více informací ZDE
Induction chemotherapy with cisplatin and fluorouracil alone or in combination with docetaxel in locally advanced squamous-cell cancer of the head and neck: long-term results of the TAX 324 randomised phase 3 trial.
Lancet Oncol. 2011 Feb;12(2):153-9. Epub 2011 Jan 11.
Více informací ZDE
Concomitant Cisplatin and Hyperfractionated Radiotherapy in Locally Advanced Head and Neck Cancer: 10-Year Follow-up of a Randomized Phase III Trial (SAKK 10/94).
Int J Radiat Oncol Biol Phys. 2011 Feb 16. [Epub ahead of print].
Více informací ZDE
Acute Toxicity Profile and Compliance to Accelerated Radiotherapy Plus Carbogen and Nicotinamide for Clinical Stage T2-4 Laryngeal Cancer: Results of a Phase III Randomized Trial.
Int J Radiat Oncol Biol Phys. 2011 Feb 5. [Epub ahead of print].
Více informací ZDE
Randomized Controlled Trial of Forward-Planned Intensity-Modulated Radiotherapy for Early Breast Cancer: Interim Results at 2 Years.
Int J Radiat Oncol Biol Phys. 2011 Feb 22. [Epub ahead of print].
Více informací ZDE
Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial.
Lancet Oncol. 2011 Feb;12(2):127-36. Epub 2011 Jan 12.
Více informací ZDE
A prospective randomized trial for postoperative vs. preoperative adjuvant radiotherapy for muscle-invasive bladder cancer.
Urol Oncol. 2011 Feb 24. [Epub ahead of print].
Více informací ZDE
Two-year results from a Swedish study on conventional versus accelerated radiotherapy in head and neck squamous cell carcinoma - The ARTSCAN study.
Radiother Oncol. 2011 Feb 3. [Epub ahead of print.
Více informací ZDE
Reirradiation of metastatic spinal cord compression: definitive results of two randomized trials.
Radiother Oncol. 2011 Feb;98(2):234-7. Epub 2011 Feb 3.
Více informací ZDE
Randomized Trial of Oral Misoprostol Treatment for Cervical Ripening before Tandem Application in Cervix Cancer.
Int J Radiat Oncol Biol Phys. 2011 Mar 4. [Epub ahead of print].
Více informací ZDE
Optimization of high-dose-rate intracavitary brachytherapy schedule in the treatment of carcinoma of the cervix.
Brachytherapy. 2011 Mar-Apr;10(2):147-53. Epub 2010 Aug 4.
Více informací ZDE
Dose escalation and quality of life in patients with localized prostate cancer treated with radiotherapy: long-term results of the Dutch randomized dose-escalation trial (CKTO 96-10 trial)..
Int J Radiat Oncol Biol Phys. 2011 Mar 15;79(4):1004-12. Epub 2010 Apr 24.
Více informací ZDE
Acute and late toxicity in a randomized trial of conventional versus hypofractionated three-dimensional conformal radiotherapy for prostate cancer.
Int J Radiat Oncol Biol Phys. 2011 Mar 15;79(4):1013-21. Epub 2010 May 5.
Více informací ZDE
Intra-operative radiotherapy of rectal cancer: Results of the French multi-institutional randomized study.
Radiother Oncol. 2011 Mar;98(3):298-303. Epub 2011 Feb 19.
Více informací ZDE
Long-term failure patterns and survival in a randomized dose-escalation trial for prostate cancer. Who dies of disease?
Int J Radiat Oncol Biol Phys. 2011 Apr 1;79(5):1310-7. Epub 2010 May 20.
Více informací ZDE
Randomized double-blind placebo-controlled trial of bevacizumab therapy for radiation necrosis of the central nervous system.
Int J Radiat Oncol Biol Phys. 2011 Apr 1;79(5):1487-95.
Více informací ZDE
Mometasone Furoate Effect on Acute Skin Toxicity in Breast Cancer Patients Receiving Radiotherapy: A Phase III Double-Blind, Randomized Trial From the North Central Cancer Treatment Group N06C4.
Int J Radiat Oncol Biol Phys. 2011 Apr 1;79(5):1460-6. Epub 2010 Aug 26.
Více informací ZDE
Residual prostate cancer in patients treated with endocrine therapy with or without radical radiotherapy: a side study of the SPCG-7 randomized trial.
Int J Radiat Oncol Biol Phys. 2011 May 1;80(1):55-61.
Více informací ZDE
Short-term neoadjuvant androgen deprivation and radiotherapy for locally advanced prostate cancer: 10-year data from the TROG 96.01 randomised trial.
Lancet Oncol. 2011 May;12(5):451-9.
Více informací ZDE
Can we decrease the skin reaction in breast cancer patients using hyaluronic acid during radiation therapy? Results of phase III randomised trial.
Radiother Oncol. 2011 May 31. [Epub ahead of print].
Více informací ZDE
Omitting elective nodal irradiation and irradiating postinduction versus preinduction chemotherapy tumor extent for limited-stage small cell lung cancer: Interim analysis of a prospective randomized noninferiority trial.
Cancer. 2011 May 19. doi: 10.1002/cncr.26119. [Epub ahead of print].
Více informací ZDE
Low or High Fractionation Dose β-Radiotherapy for Pterygium? A Randomized Clinical Trial.
Int J Radiat Oncol Biol Phys. 2011 May 17. [Epub ahead of print].
Více informací ZDE
Long-term outcome and quality of life of patients with endometrial carcinoma treated with or without pelvic radiotherapy in the post operative radiation therapy in endometrial carcinoma 1 (PORTEC-1) trial.
J Clin Oncol. 2011 May 1;29(13):1692-700. Epub 2011 Mar 28.
Více informací ZDE
Comparison of Prophylactic Naftopidil, Tamsulosin, and Silodosin for (125)I Brachytherapy-Induced Lower Urinary Tract Symptoms in Patients with Prostate Cancer: Randomized Controlled Trial.
Int J Radiat Oncol Biol Phys. 2011 Jun 8. [Epub ahead of print].
Více informací ZDE
International Phase III Trial Assessing Neoadjuvant Cisplatin, Methotrexate, and Vinblastine Chemotherapy for Muscle-Invasive Bladder Cancer: Long-Term Results of the BA06 30894 Trial.
J Clin Oncol. 2011 Jun 1;29(16):2171-7. Epub 2011 Apr 18.
Více informací ZDE
Treatment of Acute Radiodermatitis with an Oil-in-Water Emulsion Following Radiation Therapy for Breast Cancer : A Controlled, Randomized Trial.
Strahlenther Onkol. 2011 Jun;187(6):378-84. Epub 2011 May 16.
Více informací ZDE
Fifteen-Year Radiotherapy Outcomes of the Randomized PORTEC-1 Trial for Endometrial Carcinoma.
Int J Radiat Oncol Biol Phys. 2011 Jun 1. [Epub ahead of print].
Více informací ZDE
External Pelvic and Vaginal Irradiation Versus Vaginal Irradiation Alone as Postoperative Therapy in Medium-risk Endometrial Carcinoma-A Prospective Randomized Study.
Int J Radiat Oncol Biol Phys. 2011 Jun 13. [Epub ahead of print].
Více informací ZDE
Primary Tumor Response to Preoperative Chemoradiation With or Without Oxaliplatin in Locally Advanced Rectal Cancer: Pathologic Results of the STAR-01 Randomized Phase III Trial.
Clin Oncol. 2011 May 23. [Epub ahead of print].
Více informací ZDE
Phase III, open-label, randomized study comparing concurrent gemcitabine plus cisplatin and radiation followed by adjuvant gemcitabine and cisplatin versus concurrent cisplatin and radiation in patients with stage IIB to IVA carcinoma of the cervix.
J Clin Oncol. 2011 May 1;29(13):1678-85. Epub 2011 Mar 28.
Více informací ZDE
Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer: 12-year follow-up of the multicentre, randomised controlled TME trial.
Lancet Oncol. 2011 Jun;12(6):575-582. Epub 2011 May 17.
Více informací ZDE
Long-term results of a randomized trial on the sequencing of radiotherapy and chemotherapy in breast cancer.
Am J Clin Oncol. 2011 Jun;34(3):238-44.
Více informací ZDE
Long-term outcomes of invasive ipsilateral breast tumor recurrences after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS.
J Natl Cancer Inst. 2011 Mar 16;103(6):478-88. Epub 2011 Mar 11.
Více informací ZDE
Reduced dose radiotherapy for local control in non-Hodgkin lymphoma: A randomised phase III trial.
Radiother Oncol. 2011 Jun 9. [Epub ahead of print].
Více informací ZDE
Palifermin Reduces Severe Mucositis in Definitive Chemoradiotherapy of Locally Advanced Head and Neck Cancer: A Randomized, Placebo-Controlled Study.
J Clin Oncol. 2011 Jun 13. [Epub ahead of print].
Více informací ZDE
Palifermin Decreases Severe Oral Mucositis of Patients Undergoing Postoperative Radiochemotherapy for Head and Neck Cancer: A Randomized, Placebo-Controlled Trial.
Clin Oncol. 2011 Jun 13. [Epub ahead of print].
Více informací ZDE
70 Gy Versus 80 Gy in Localized Prostate Cancer: 5-Year Results of GETUG 06 Randomized Trial.
Int J Radiat Oncol Biol Phys. 2011 Jul 15;80(4):1056-63. Epub 2010 Dec 14.
Více informací ZDE
Phase III randomized equivalence trial of early breast cancer treatments with or without axillary clearance in post-menopausal patients results after 5 years of follow-up.
Eur J Surg Oncol. 2011 Jul;37(7):563-570. Epub 2011 Jun 12.
Více informací ZDE
Radiotherapy and short-term androgen deprivation for localized prostate cancer.
N Engl J Med. 2011 Jul 14;365(2):107-18.
Více informací ZDE
Randomized clinical trial of postoperative strontium-90 radiation therapy for pterygia: treatment using 30 Gy/3 fractions vs. 40 Gy/4 fractions.
Strahlenther Onkol. 2011 Jul;187(7):401-5. Epub 2011 Jun 27.
Více informací ZDE
Adjuvant prophylactic regional radiotherapy versus observation in stage I Merkel cell carcinoma: a multicentric prospective randomized study.
Ann Oncol. 2011 Jul 12. [Epub ahead of print].
Více informací ZDE
The influence of HPV-associated p16-expression on accelerated fractionated radiotherapy in head and neck cancer: Evaluation of the randomised DAHANCA 6&7 trial.
Radiother Oncol. 2011 Jul;100(1):49-55. Epub 2011 Mar 21.
Více informací ZDE
Accelerated radiotherapy and concomitant high dose chemotherapy in non resectable stage IV locally advanced HNSCC: Results of a GORTEC randomized trial.
Radiother Oncol. 2011 Jul;100(1):56-61. Epub 2011 Aug 8.
Více informací ZDE
Randomized phase III trial (GORTEC 98-03) comparing re-irradiation plus chemotherapy versus methotrexate in patients with recurrent or a second primary head and neck squamous cell carcinoma, treated with a palliative intent.
Radiother Oncol. 2011 Jul;100(1):70-5. Epub 2011 Jul 7.
Více informací ZDE
Final results of the randomized phase III CHARTWEL-trial (ARO 97-1) comparing hyperfractionated-accelerated versus conventionally fractionated radiotherapy in non-small cell lung cancer (NSCLC).
Radiother Oncol. 2011 Jul;100(1):76-85. Epub 2011 Jul 13.
Více informací ZDE
First results of the randomised UK FAST Trial of radiotherapy hypofractionation for treatment of early breast cancer (CRUKE/04/015).
Radiother Oncol. 2011 Jul;100(1):93-100.
Více informací ZDE
Does transfusion improve the outcome for HNSCC patients treated with radiotherapy? - Results from the randomized DAHANCA 5 and 7 trials.
Acta Oncol. 2011 Oct;50(7):1006-14. Epub 2011 Jul 26.
Více informací ZDE
A Randomized Controlled Trial of Conventional Fraction and Late Course Accelerated Hyperfraction Three-Dimensional Conformal Radiotherapy for Esophageal Cancer.
Cell Biochem Biophys. 2011 Aug 20. [Epub ahead of print].
Více informací ZDE
Randomized Phase III Trial of Sequential Adjuvant Chemoradiotherapy With or Without Erythropoietin Alfa in Patients With High-Risk Cervical Cancer: Results of the NOGGO-AGO Intergroup Study.
J Clin Oncol. 2011 Aug 22. [Epub ahead of print].
Více informací ZDE
Persistent pain after targeted intraoperative radiotherapy (TARGIT) or external breast radiotherapy for breast cancer: A randomized trial.
Breast. 2011 Aug 22. [Epub ahead of print].
Více informací ZDE
Randomized Clinical Trial of Weekly vs. Triweekly Cisplatin-Based Chemotherapy Concurrent with Radiotherapy in the Treatment of Locally Advanced Cervical Cancer.
Int J Radiat Oncol Biol Phys. 2011 Aug 11. [Epub ahead of print].
Více informací ZDE
Five-year quality of life results of the randomized clinical phase III (RADPLAT) trial, comparing concomitant intra-arterial versus intravenous chemoradiotherapy in locally advanced head and neck cancer.
Head Neck. 2011 Aug 4. doi: 10.1002/hed.21851. [Epub ahead of print].
Více informací ZDE
Adjuvant chemotherapy and radiotherapy in triple-negative breast carcinoma: A prospective randomized controlled multi-center trial.
Radiother Oncol. 2011 Aug;100(2):200-4. Epub 2011 Aug 16.
Více informací ZDE
A randomised trial of Supine versus Prone breast radiotherapy (SuPr study): Comparing set-up errors and respiratory motion.
Radiother Oncol. 2011 Aug;100(2):221-6. Epub 2010 Dec 13.
Více informací ZDE
A randomized trial (Irish clinical oncology research group 97-01) comparing short versus protracted neoadjuvant hormonal therapy before radiotherapy for localized prostate cancer.
Int J Radiat Oncol Biol Phys. 2011 Sep 1;81(1):35-45. Epub 2010 Aug 25.
Více informací ZDE
Sequential vs Concurrent Chemoradiation for Stage III Non-Small Cell Lung Cancer: Randomized Phase III Trial RTOG 9410.
J Natl Cancer Inst. 2011 Sep 8. [Epub ahead of print].
Více informací ZDE
Initial results of a randomised controlled trial comparing clinical and pathological downstaging of rectal cancer after preoperative short-course radiotherapy or long term chemoradiotherapy both with delayed surgery.
Colorectal Dis. 2011 Sep 8. doi: 10.1111/j.1463-1318.2011.02815.x. [Epub ahead of print].
Více informací ZDE
Induction chemotherapy and continuous hyperfractionated accelerated radiotherapy (chart) for patients with locally advanced inoperable non-small-cell lung cancer: the MRC INCH randomized trial.
Int J Radiat Oncol Biol Phys. 2011 Nov 1;81(3):712-8. Epub 2010 Oct 6.
Více informací ZDE
Phase III study of radiation therapy with or without cis-platinum in patients with unresectable squamous or undifferentiated carcinoma of the head and neck: an intergroup trial of the Eastern Cooperative Oncology Group (E2382)..
Int J Radiat Oncol Biol Phys. 2011 Nov 1;81(3):719-25. Epub 2010 Oct 1.
Více informací ZDE
Randomized trial of postoperative adjuvant therapy in Stage II and III rectal cancer to define the optimal sequence of chemotherapy and radiotherapy: 10-year follow-up.
Int J Radiat Oncol Biol Phys. 2011 Nov 15;81(4):1025-31. Epub 2010 Oct 6.
Více informací ZDE
Late patient-reported toxicity after preoperative radiotherapy or chemoradiotherapy in nonresectable rectal cancer: results from a randomized Phase III study.
Int J Radiat Oncol Biol Phys. 2011 Nov 15;81(4):1017-24. Epub 2010 Oct 6.
Více informací ZDE
Pulmonary toxicity in Stage III non-small cell lung cancer patients treated with high-dose (74 Gy) 3-dimensional conformal thoracic radiotherapy and concurrent chemotherapy following induction chemotherapy: a secondary analysis of Cancer and Leukemia Group B (CALGB) trial 30105.
Int J Radiat Oncol Biol Phys. 2011 Nov 15;81(4):e269-74. Epub 2011 Apr 7.
Více informací ZDE
Randomized clinical trial on preoperative radiotherapy 25 Gy in rectal cancer-treatment results at 5-year follow-up.
Langenbecks Arch Surg. 2011 Dec 15. [Epub ahead of print].
Více informací ZDE
Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: preliminary safety results from the CHHiP randomised controlled trial.
Lancet Oncol. 2011 Dec 12. [Epub ahead of print].
Více informací ZDE
Concurrent chemoradiotherapy plus adjuvant chemotherapy versus concurrent chemoradiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 3 multicentre randomised controlled trial.
Lancet Oncol. 2011 Dec 7. [Epub ahead of print].
Více informací ZDE
Concurrent Chemoradiotherapy vs Radiotherapy Alone in Stage II Nasopharyngeal Carcinoma: Phase III Randomized Trial.
J Natl Cancer Inst. 2011 Dec 7;103(23):1761-70. Epub 2011 Nov 4.
Více informací ZDE
